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12/25/2023 12:28:03 PM | Browse: 367 | Download: 1279
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Received |
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2023-09-11 09:20 |
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Peer-Review Started |
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2023-09-11 09:22 |
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First Decision by Editorial Office Director |
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2023-10-09 08:13 |
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Return for Revision |
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2023-10-09 08:13 |
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Revised |
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2023-10-19 04:05 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2023-11-16 02:14 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2023-11-30 06:23 |
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Articles in Press |
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2023-11-30 06:23 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-12-18 10:00 |
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Publish the Manuscript Online |
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2023-12-25 12:17 |
| ISSN |
2220-3249 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Perilipin2 inhibits the replication of hepatitis B virus deoxyribonucleic acid by regulating autophagy under high-fat conditions
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Chuang Wang, Xiao-Yun Gao, Mei Han, Meng-Chun Jiang, Xiao-Yi Shi, Chun-Wen Pu and Xuan Du |
| Funding Agency and Grant Number |
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| Corresponding Author |
Xuan Du, PhD, Doctor, Doctor, Department of Gastroenterology, The Second Affiliated Hospital of Dalian Medical University, No. 467 Zhongshan Road, Shahekou District, Dalian 116023, Liaoning Province, China. duxuan945@163.com |
| Key Words |
Lipid metabolism; Chronic HBV infection; Nonalcoholic fatty liver; Plin2; Autophagy |
| Core Tip |
Our data suggest that fatty acid stimulation inhibits hepatitis B virus (HBV) replication by upregulating Plin2 expression, inhibiting hepatocyte autophagy. This process associates with lipid metabolism, autophagy pathway, and HBV replication. Further study of lipid metabolism-Plin2-autophagy is important to understand HBV host interactions and pathogenesis better and suggests a possible route for treating patients with chronic HBV infection combined with nonalcoholic fatty liver disease. |
| Publish Date |
2023-12-25 12:17 |
| Citation |
Wang C, Gao XY, Han M, Jiang MC, Shi XY, Pu CW, Du X. Perilipin2 inhibits the replication of hepatitis B virus deoxyribonucleic acid by regulating autophagy under high-fat conditions. World J Virol 2023; 12(5): 296-308 |
| URL |
https://www.wjgnet.com/2220-3249/full/v12/i5/296.htm |
| DOI |
https://dx.doi.org/10.5501/wjv.v12.i5.296 |
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