Publication Name	World Journal of Experimental Medicine
Manuscript ID	87202
Country	India

Received	2023-07-28 19:01
Peer-Review Started	2023-07-28 19:04
To Make the First Decision
Return for Revision	2023-09-05 03:23
Revised	2023-10-04 16:30
Second Decision	2024-01-05 02:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-01-05 06:17
Articles in Press	2024-01-05 06:17
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-01-04 02:06
Typeset the Manuscript	2024-02-18 03:41
Publish the Manuscript Online	2024-03-19 14:54

ISSN	2220-315x (online)
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Category	Medicine, Research & Experimental
Manuscript Type	Minireviews
Article Title	Emerging significance of butyrylcholinesterase
Manuscript Source	Invited Manuscript
All Author List	Gumpeny R Sridhar and Lakshmi Gumpeny
Funding Agency and Grant Number
Corresponding Author	Gumpeny R Sridhar, FRCP, Adjunct Professor, Department of Endocrinology and Diabetes, Endocrine and Diabetes Centre, 15-12-15 Krishnanagar, Visakhapatnam 530002, Andhra Pradesh, India. sridharvizag@gmail.com
Key Words	Esterase; Acetylcholinesterase; Variant; Cholinergic; Metabolic syndrome; Cognition; Knockout model
Core Tip	Butyrylcholinesterase (BChE), a hepatic enzyme, hydrolyzes the muscle relaxant succinylcholine. Individuals with variant forms of the enzyme are healthy until they are administered succinylcholine during anesthesia. The enzyme may have regulatory roles in lipid metabolism, cholinergic response, and Alzheimer’s disease. People with variant forms of the enzyme are natural human knockout models and can be followed up to study the metabolic impact of harboring variant forms of BChE.
Publish Date	2024-03-19 14:54
Citation	Sridhar GR, Gumpeny L. Emerging significance of butyrylcholinesterase. World J Exp Med 2024; 14(1): 87202
URL	https://www.wjgnet.com/2220-315x/full/v14/i1/87202.htm
DOI	https://dx.doi.org/10.5493/wjem.v14.i1.87202

Full Article (PDF)	WJEM-14-87202-with-cover.pdf
Manuscript File	87202_Auto_Edited-LJH_WangTQ-JLW.docx
Answering Reviewers	87202-Answering reviewers.pdf
Audio Core Tip	87202-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	87202-Conflict-of-interest statement.pdf
Copyright License Agreement	87202-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	87202-Language certificate.pdf
Peer-review Report	87202-Peer-review(s).pdf
Scientific Misconduct Check	87202-Bing-Liu JH-2.png
Scientific Misconduct Check	87202-CrossCheck.png
Scientific Editor Work List	87202-Scientific editor work list.pdf