Publication Name	World Journal of Gastroenterology
Manuscript ID	87294
Country	China

Received	2023-08-07 09:28
Peer-Review Started	2023-08-04 02:08
To Make the First Decision
Return for Revision	2023-10-25 05:59
Revised	2023-11-07 02:36
Second Decision	2023-12-01 02:31
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-12-08 03:29
Articles in Press	2023-12-08 03:29
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-12-15 02:05
Publish the Manuscript Online	2023-12-19 02:09

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Risk factors and a predictive nomogram for lymph node metastasis in superficial esophageal squamous cell carcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Jin Wang, Xian Zhang, Tao Gan, Ni-Ni Rao, Kai Deng and Jin-Lin Yang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82173253 Sichuan Province Science and Technology Support Program 2022YFH0003 Postdoctoral Research Foundation of West China Hospital No. 2021HXBH020 The Medico- Engineering Cooperation Funds from the University of Electronic Science and Technology of China and West China Hospital of Sichuan University HXDZ22005 Sichuan Province Science and Technology Support Program 2023NSFSC1900
Corresponding Author	Jin-Lin Yang, MD, PhD, Chief Physician, Professor, Department of Gastroenterology and Hepatology, Sichuan University-University of Oxford Huaxi Joint Centre for Gastrointestinal Cancer, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, No.37 Guoxue Road, Wuhou District, Chengdu 610041, Sichuan Province, China. yangjinlin@wchscu.cn
Key Words	Superficial esophageal squamous cell carcinoma; Lymph node metastasis; Risk factors; Nomogram; Predictive model
Core Tip	This is a retrospective study to identify risk factors for lymph node metastasis (LNM) in superficial esophageal squamous cell carcinoma (ESCC) and to develop a nomogram model for predicting LNM. A total of 474 superficial ESCC patients who underwent esophagectomy were enrolled. Multivariate logistic analysis showed that tumor size, invasive depth, tumor differentiation, infiltrative growth pattern, tumor budding, and lymphovascular invasion were significantly correlated with LNM. A predictive nomogram using these six variables showed good performance and will facilitate the treatment choice for superficial ESCC patients.
Publish Date	2023-12-19 02:09
Citation	Wang J, Zhang X, Gan T, Rao NN, Deng K, Yang JL. Risk factors and a predictive nomogram for lymph node metastasis in superficial esophageal squamous cell carcinoma. World J Gastroenterol 2023; 29(47): 6138-6147
URL	https://www.wjgnet.com/1007-9327/full/v29/i47/6138.htm
DOI	https://dx.doi.org/10.3748/wjg.v29.i47.6138

Full Article (PDF)	WJG-29-6138-with-cover.pdf
Full Article (Word)	WJG-29-6138.docx
Manuscript File	87294_Auto_Edited-JLW.docx
Answering Reviewers	87294-Answering reviewers.pdf
Audio Core Tip	87294-Audio core tip.mp3
Biostatistics Review Certificate	87294-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	87294-Conflict-of-interest statement.pdf
Copyright License Agreement	87294-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	87294-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	87294-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	87294-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	87294-Language certificate.pdf
Peer-review Report	87294-Peer-review(s).pdf
Scientific Misconduct Check	87294-Bing-Yan JP-2.png
Scientific Editor Work List	87294-Scientific editor work list.pdf
CrossCheck Report	87294-CrossCheck report.pdf