| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Systematic sequential therapy for ex vivo liver resection and autotransplantation: A case report and review of the literature
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Chen-Lu Hu, Xin Han, Zhen-Zhen Gao, Bo Zhou, Jin-Long Tang, Xiang-Ru Pei, Jie-Nan Lu, Qin Xu, Xiao-Ping Shen, Sheng Yan and Yuan Ding |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Yuan Ding, Doctor, MD, Academic Editor, Chief Physician, Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, No. 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China. dingyuan@zju.edu.cn |
| Key Words |
Perihilar cholangiocarcinoma; Ex vivo liver resection and autotransplantation; Systemic sequential therapy; Conversion therapy; Case report |
| Core Tip |
Limited by tumor’s anatomic location and peri-vascular invasion, most perihilar cholangiocarcinoma patients lose the chance for curative treatment. In this case, we originally put forward systematic conversion therapy followed by ex vivo liver resection and autotransplantation (ELRA). The patient achieved partial response after three cycles of systemic sequential treatment without severe toxicities. Soon afterwards, ELRA, anastomotic reconstruction of the middle hepatic vein, the right hepatic vein, the root of portal vein, inferior vena cava and right hepatic artery, and lymph node dissection were performed with success. The patient achieved long time survival and has survived 22 mo following diagnosis with no evidence of recurrence or metastasis. |
| Publish Date |
2023-11-27 10:26 |
| Citation |
Hu CL, Han X, Gao ZZ, Zhou B, Tang JL, Pei XR, Lu JN, Xu Q, Shen XP, Yan S, Ding Y. Systematic sequential therapy for ex vivo liver resection and autotransplantation: A case report and review of literature. World J Gastrointest Surg 2023; 15(11): 2663-2673 |
| URL |
https://www.wjgnet.com/1948-9366/full/v15/i11/2663.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v15.i11.2663 |
