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12/19/2023 1:25:00 PM | Browse: 353 | Download: 1407
Publication Name World Journal of Psychiatry
Manuscript ID 87839
Country China
Received
2023-08-31 08:12
Peer-Review Started
2023-08-31 08:15
First Decision by Editorial Office Director
2023-09-14 07:17
Return for Revision
2023-09-14 07:17
Revised
2023-10-13 06:30
Publication Fee Transferred
Second Decision by Editor
2023-11-03 00:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2023-11-09 06:45
Articles in Press
2023-11-09 06:45
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-12-11 08:41
Publish the Manuscript Online
2023-12-19 13:19
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Case Control Study
Article Title Haplotype analysis of long-chain non-coding RNA NONHSAT102891 promoter polymorphisms and depression in Chinese individuals: A case-control association study
Manuscript Source Unsolicited Manuscript
All Author List Yue Li, Yi-Xi Wang, Xing-Ming Tang, Peng Liang, Jing-Jie Chen, Feng Jiang, Qiang Yang and Yun-Dan Liang
Funding Agency and Grant Number
Funding Agency Grant Number
Chengdu Medical College Graduate Research Innovation Fund Project No. YCX2023-01-03
National Natural Science Foundation of China No. 81901379
National Undergraduate Training Program for Innovation and Entrepreneurship No. 202113705034
Corresponding Author Yun-Dan Liang, PhD, Adjunct Associate Professor, Associate Professor, Department of Pathology and Pathophysiology, Chengdu Medical College, No. 783 Xindu Avenue, Chengdu 610500, Sichuan Province, China. liangyundan2004@126.com
Key Words Long-chain non-coding RNA NONHSAT102891; Depression; Susceptibility; Single-nucleotide polymorphisms; Haplotype; Transcriptional activity
Core Tip Depression has risen to the top of the global burden of non-fatal diseases. Recently, emerging evidence supports long-chain non-coding RNA (lncRNA) may be involved in the occurrence and development of depression, and may serve as potential diagnostic and prognostic markers. Our previous study showed lncRNA NONHSAT102891 rs155979 GC affects depression susceptibility; this study genotyped 480 depression patients and 329 healthy controls for the two single-nucleotide polymorphisms and made dual-luciferase reporter assays to explore and elucidate the function of the two lncRNA NONHSAT102891 promoter G/C and A/T haplotypes. We found the rs6230 and rs3792747 CG haplotypes may reduce the risk of depression, and expands our knowledge about this disease.
Publish Date 2023-12-19 13:19
Citation Li Y, Wang YX, Tang XM, Liang P, Chen JJ, Jiang F, Yang Q, Liang YD. Haplotype analysis of long-chain non-coding RNA NONHSAT102891 promoter polymorphisms and depression in Chinese individuals: A case-control association study. World J Psychiatry 2023; 13(12): 1005-1015
URL https://www.wjgnet.com/2220-3206/full/v13/i12/1005.htm
DOI https://dx.doi.org/10.5498/wjp.v13.i12.1005
Full Article (PDF) WJP-13-1005-with-cover.pdf
Full Article (Word) WJP-13-1005.docx