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12/19/2023 1:25:00 PM | Browse: 178 | Download: 626
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Received |
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2023-08-31 08:12 |
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Peer-Review Started |
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2023-08-31 08:15 |
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To Make the First Decision |
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Return for Revision |
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2023-09-14 07:17 |
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Revised |
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2023-10-13 06:30 |
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Second Decision |
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2023-11-03 00:39 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-11-09 06:45 |
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Articles in Press |
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2023-11-09 06:45 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-12-11 08:41 |
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Publish the Manuscript Online |
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2023-12-19 13:19 |
ISSN |
2220-3206 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Psychiatry |
Manuscript Type |
Case Control Study |
Article Title |
Haplotype analysis of long-chain non-coding RNA NONHSAT102891 promoter polymorphisms and depression in Chinese individuals: A case-control association study
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Yue Li, Yi-Xi Wang, Xing-Ming Tang, Peng Liang, Jing-Jie Chen, Feng Jiang, Qiang Yang and Yun-Dan Liang |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Chengdu Medical College Graduate Research Innovation Fund Project |
No. YCX2023-01-03 |
National Natural Science Foundation of China |
No. 81901379 |
National Undergraduate Training Program for Innovation and Entrepreneurship |
No. 202113705034 |
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Corresponding Author |
Yun-Dan Liang, PhD, Adjunct Associate Professor, Associate Professor, Department of Pathology and Pathophysiology, Chengdu Medical College, No. 783 Xindu Avenue, Chengdu 610500, Sichuan Province, China. liangyundan2004@126.com |
Key Words |
Long-chain non-coding RNA NONHSAT102891; Depression; Susceptibility; Single-nucleotide polymorphisms; Haplotype; Transcriptional activity |
Core Tip |
Depression has risen to the top of the global burden of non-fatal diseases. Recently, emerging evidence supports long-chain non-coding RNA (lncRNA) may be involved in the occurrence and development of depression, and may serve as potential diagnostic and prognostic markers. Our previous study showed lncRNA NONHSAT102891 rs155979 GC affects depression susceptibility; this study genotyped 480 depression patients and 329 healthy controls for the two single-nucleotide polymorphisms and made dual-luciferase reporter assays to explore and elucidate the function of the two lncRNA NONHSAT102891 promoter G/C and A/T haplotypes. We found the rs6230 and rs3792747 CG haplotypes may reduce the risk of depression, and expands our knowledge about this disease. |
Publish Date |
2023-12-19 13:19 |
Citation |
Li Y, Wang YX, Tang XM, Liang P, Chen JJ, Jiang F, Yang Q, Liang YD. Haplotype analysis of long-chain non-coding RNA NONHSAT102891 promoter polymorphisms and depression in Chinese individuals: A case-control association study. World J Psychiatry 2023; 13(12): 1005-1015 |
URL |
https://www.wjgnet.com/2220-3206/full/v13/i12/1005.htm |
DOI |
https://dx.doi.org/10.5498/wjp.v13.i12.1005 |
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