Publication Name	World Journal of Psychiatry
Manuscript ID	87839
Country	China

Received	2023-08-31 08:12
Peer-Review Started	2023-08-31 08:15
To Make the First Decision
Return for Revision	2023-09-14 07:17
Revised	2023-10-13 06:30
Second Decision	2023-11-03 00:39
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-11-09 06:45
Articles in Press	2023-11-09 06:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-12-11 08:41
Publish the Manuscript Online	2023-12-19 13:19

ISSN	2220-3206 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Psychiatry
Manuscript Type	Case Control Study
Article Title	Haplotype analysis of long-chain non-coding RNA NONHSAT102891 promoter polymorphisms and depression in Chinese individuals: A case-control association study
Manuscript Source	Unsolicited Manuscript
All Author List	Yue Li, Yi-Xi Wang, Xing-Ming Tang, Peng Liang, Jing-Jie Chen, Feng Jiang, Qiang Yang and Yun-Dan Liang
Funding Agency and Grant Number	Funding Agency Grant Number Chengdu Medical College Graduate Research Innovation Fund Project No. YCX2023-01-03 National Natural Science Foundation of China No. 81901379 National Undergraduate Training Program for Innovation and Entrepreneurship No. 202113705034
Corresponding Author	Yun-Dan Liang, PhD, Adjunct Associate Professor, Associate Professor, Department of Pathology and Pathophysiology, Chengdu Medical College, No. 783 Xindu Avenue, Chengdu 610500, Sichuan Province, China. liangyundan2004@126.com
Key Words	Long-chain non-coding RNA NONHSAT102891; Depression; Susceptibility; Single-nucleotide polymorphisms; Haplotype; Transcriptional activity
Core Tip	Depression has risen to the top of the global burden of non-fatal diseases. Recently, emerging evidence supports long-chain non-coding RNA (lncRNA) may be involved in the occurrence and development of depression, and may serve as potential diagnostic and prognostic markers. Our previous study showed lncRNA NONHSAT102891 rs155979 GC affects depression susceptibility; this study genotyped 480 depression patients and 329 healthy controls for the two single-nucleotide polymorphisms and made dual-luciferase reporter assays to explore and elucidate the function of the two lncRNA NONHSAT102891 promoter G/C and A/T haplotypes. We found the rs6230 and rs3792747 CG haplotypes may reduce the risk of depression, and expands our knowledge about this disease.
Publish Date	2023-12-19 13:19
Citation	Li Y, Wang YX, Tang XM, Liang P, Chen JJ, Jiang F, Yang Q, Liang YD. Haplotype analysis of long-chain non-coding RNA NONHSAT102891 promoter polymorphisms and depression in Chinese individuals: A case-control association study. World J Psychiatry 2023; 13(12): 1005-1015
URL	https://www.wjgnet.com/2220-3206/full/v13/i12/1005.htm
DOI	https://dx.doi.org/10.5498/wjp.v13.i12.1005

Full Article (PDF)	WJP-13-1005-with-cover.pdf
Full Article (Word)	WJP-13-1005.docx
STROBE Statement	87839-STROBE statement.pdf
Manuscript File	87839_Auto_Edited-JLW.docx
Answering Reviewers	87839-Answering reviewers.pdf
Audio Core Tip	87839-Audio core tip.mp3
Biostatistics Review Certificate	87839-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	87839-Conflict-of-interest statement.pdf
Copyright License Agreement	87839-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	87839-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	87839-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	87839-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	87839-Language certificate.pdf
Peer-review Report	87839-Peer-review(s).pdf
Scientific Misconduct Check	87839-Bing-Qu XL-2.jpg
Scientific Editor Work List	87839-Scientific editor work list.pdf