Publication Name	World Journal of Radiology
Manuscript ID	87987
Country	Canada

Received	2023-09-06 13:25
Peer-Review Started	2023-09-06 13:27
To Make the First Decision
Return for Revision	2023-09-19 07:04
Revised	2023-09-20 15:53
Second Decision	2023-09-28 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-09-28 05:48
Articles in Press	2023-09-28 05:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-10-23 01:33
Publish the Manuscript Online	2023-10-24 07:40

ISSN	1949-8470 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Retrospective Study
Article Title	Two-point Dixon and six-point Dixon magnetic resonance techniques in the detection, quantification and grading of hepatic steatosis
Manuscript Source	Unsolicited Manuscript
All Author List	Mohamed Elfaal, Alanna Supersad, Craig Ferguson, Stephanie Locas, Florin Manolea, Mitchell P Wilson, Medica Sam, Wendy Tu and Gavin Low
Funding Agency and Grant Number
Corresponding Author	Gavin Low, MBChB, MPhil, Professor, Department of Radiology & Diagnostic Imaging, University of Alberta, WMC 2B2.41 8440-112 ST, Edmonton T6G2B7, Alberta, Canada. gavinlow@mic.ca
Key Words	Chemical shift encoded Dixon magnetic resonance techniques; Hepatic steatosis; Liver fat quantification; Magnetic resonance spectroscopy; Proton density fat fraction; Ultrasound
Core Tip	Fat fraction (FF) estimates on the Dixon techniques (two-point Dixon and six-point Dixon) have excellent correlation with magnetic resonance spectroscopy-proton density FF (MRS-PDFF), and excellent accuracy in detecting steatosis, and grading severe steatosis. However, in iron overload, two-point Dixon was not evaluable due to confounding effect on liver signal from T2* decay. The excellent correlation between the Dixon techniques vs MRS-PDFF was not affected by co-existing liver fibrosis.
Publish Date	2023-10-24 07:40
Citation	Elfaal M, Supersad A, Ferguson C, Locas S, Manolea F, Wilson MP, Sam M, Tu W, Low G. Two-point Dixon and six-point Dixon magnetic resonance techniques in the detection, quantification and grading of hepatic steatosis. World J Radiol 2023; 15(10): 293-303
URL	https://www.wjgnet.com/1949-8470/full/v15/i10/293.htm
DOI	https://dx.doi.org/10.4329/wjr.v15.i10.293

Full Article (PDF)	WJR-15-293-with-cover.pdf
Full Article (Word)	WJR-15-293.docx
Manuscript File	87987_Auto_Edited-JLW.docx
Answering Reviewers	87987-Answering reviewers.pdf
Audio Core Tip	87987-Audio core tip.m4a
Biostatistics Review Certificate	87987-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	87987-Conflict-of-interest statement.pdf
Copyright License Agreement	87987-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	87987-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	87987-Institutional review board statement.pdf
Peer-review Report	87987-Peer-review(s).pdf
Scientific Misconduct Check	87987-Bing-Wang JJ-2.png
Scientific Editor Work List	87987-Scientific editor work list.pdf
CrossCheck Report	87987-CrossCheck report.pdf