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12/26/2023 12:35:11 PM | Browse: 260 | Download: 898
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Received |
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2023-09-06 02:41 |
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Peer-Review Started |
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2023-09-06 02:42 |
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To Make the First Decision |
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Return for Revision |
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2023-10-23 02:54 |
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Revised |
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2023-11-17 05:42 |
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Second Decision |
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2023-11-28 23:56 |
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Accepted by Journal Editor-in-Chief |
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2023-11-29 23:41 |
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Accepted by Executive Editor-in-Chief |
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2023-12-04 06:05 |
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Articles in Press |
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2023-12-04 06:05 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-12-20 12:02 |
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Publish the Manuscript Online |
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2023-12-26 02:50 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Neurosciences |
| Manuscript Type |
Basic Study |
| Article Title |
ADSC-Exos outperform BMSC-Exos in alleviating hydrostatic pressure-induced injury to retinal ganglion cells by upregulating nerve growth factors
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhi-Kun Zheng, Lei Kong, Min Dai, Yi-Dan Chen and Yan-Hua Chen |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Yunnan Provincial High-level Talent Cultivation Support Program for Young Top-notch Talents |
YNWR-QNBJ-2020-237 |
| Yunnan Natural Science Foundation |
202301AT070190 |
| Kunming Medical University Joint Special Fund |
202301AY070001-222 |
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| Corresponding Author |
Min Dai, PhD, Doctor, Doctor, Department of Ophthalmology, Affiliated Hospital of Yunnan University/Yunnan Eye Hospital, No. 176 Qingnian Road, Wuhua District, Kunming 650021, Yunnan Province, China. dm9024@163.com |
| Key Words |
Adipose-derived stem cells; Bone marrow-derived stem cells; Exosomes; Glaucoma |
| Core Tip |
We discovered for the first time that adipose-derived stem cell-exosomes (ADSC-Exos) significantly ameliorate retinal ganglion cell (RGC) injury caused by hydrostatic pressure by inhibiting apoptosis and increasing the secretion of neurotrophic factors. ADSC-Exos manifested better ameliorating effects than bone marrow-derived stem cell (BMSC)-Exos in ameliorating the RGC injury induced by hydrostatic pressure. BMSC-Exos ameliorate optic nerve injury caused by hydrostatic pressure by inhibiting apoptosis and increasing the secretion of neurotrophic factors. |
| Publish Date |
2023-12-26 02:50 |
| Citation |
Zheng ZK, Kong L, Dai M, Chen YD, Chen YH. ADSC-Exos outperform BMSC-Exos in alleviating hydrostatic pressure-induced injury to retinal ganglion cells by upregulating nerve growth factors. World J Stem Cells 2023; 15(12): 1077-1092 |
| URL |
https://www.wjgnet.com/1948-0210/full/v15/i12/1077.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v15.i12.1077 |
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