Publication Name	World Journal of Gastroenterology
Manuscript ID	88173
Country	United States

Received	2023-09-13 13:12
Peer-Review Started	2023-09-13 13:15
To Make the First Decision
Return for Revision	2023-10-17 04:02
Revised	2023-11-08 20:54
Second Decision	2023-11-23 02:11
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-12-01 07:15
Articles in Press	2023-12-01 07:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-12-07 02:03
Publish the Manuscript Online	2023-12-13 07:04

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Frailty in end-stage liver disease: Understanding pathophysiology, tools for assessment, and strategies for management
Manuscript Source	Unsolicited Manuscript
All Author List	Mazen Elsheikh, Ahmed El Sabagh, Islam B Mohamed, Megha Bhongade, Manal M Hassan and Prasun Kumar Jalal
Funding Agency and Grant Number
Corresponding Author	Mazen Elsheikh, MD, Research Assistant, Department of Gastroenterology and Hepatology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, United States. dr_mazenelsheikh@hotmail.com
Key Words	End-stage liver disease; Frailty; Liver cirrhosis; Malnutrition; Sarcopenia
Core Tip	Frailty is a common condition in patients with cirrhosis, and it is associated with increased morbidity and mortality. This review provides a comprehensive overview of the etiology, pathophysiology, assessment, and management of frailty in cirrhosis. It places particular emphasis on the management of frailty during complications, while also delving into the future of managing this condition.
Publish Date	2023-12-13 07:04
Citation	Elsheikh M, El Sabagh A, Mohamed IB, Bhongade M, Hassan MM, Jalal PK. Frailty in end-stage liver disease: Understanding pathophysiology, tools for assessment, and strategies for management. World J Gastroenterol 2023; 29(46): 6028-6048
URL	https://www.wjgnet.com/1007-9327/full/v29/i46/6028.htm
DOI	https://dx.doi.org/10.3748/wjg.v29.i46.6028

Full Article (PDF)	WJG-29-6028-with-cover.pdf
Full Article (Word)	WJG-29-6028.docx
Manuscript File	88173_Auto_Edited-JLW.docx
Answering Reviewers	88173-Answering reviewers.pdf
Audio Core Tip	88173-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	88173-Conflict-of-interest statement.pdf
Copyright License Agreement	88173-Copyright license agreement.pdf
Peer-review Report	88173-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	88173-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	88173-Bing-Gao CC-2.png
Scientific Editor Work List	88173-Scientific editor work list.pdf
CrossCheck Report	88173-CrossCheck report.pdf