Publication Name	World Journal of Clinical Cases
Manuscript ID	88717
Country	China

Received	2023-10-11 05:28
Peer-Review Started	2023-10-11 05:28
To Make the First Decision
Return for Revision	2023-11-22 02:52
Revised	2023-12-05 09:46
Second Decision	2023-12-13 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-12-13 06:50
Articles in Press	2023-12-13 06:50
Publication Fee Transferred
Edit the Manuscript by Language Editor	2023-12-18 02:20
Typeset the Manuscript	2023-12-25 02:06
Publish the Manuscript Online	2024-01-02 09:08

ISSN	2307-8960 (online)
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Category	Pathology
Manuscript Type	Case Report
Article Title	Changes in macrophage infiltration and podocyte injury in lupus nephritis patients with repeated renal biopsy: Three case reports
Manuscript Source	Unsolicited Manuscript
All Author List	Shi-Yuan Liu, Hao Chen, Li-Jia He, Chun-Kai Huang, Pu Wang, Zhang-Ru Rui, Jue Wu, Yang Yuan, Yue Zhang, Wen-Ju Wang and Xiao-Dan Wang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81960136 the Science and Technology Department of Yunnan Province 202101AT070243
Corresponding Author	Xiao-Dan Wang, MD, Associate Chief Physician, Central Laboratory, Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Hospital Affiliated to Kunming Medical University, No. 245 Renmin East Road, Kunming 650051, Yunnan Province, China. wxdky001@163.com
Key Words	Lupus nephritis; Macrophage; Podocyte; Repeat renal biopsy; Thrombotic Microangiopathy; Case report
Core Tip	In this study, we retrospectively analysed the clinical and pathological data of three patients who underwent repeated renal biopsies after treatment for diffuse proliferative lupus nephritis (LN) with different pathological characteristics. Immunohistochemistry and immunofluorescence tests were used to compare the podocyte damage and infiltration of macrophages. Diffuse proliferative LN with different pathological features has different prognoses, and the prognosis of LN with Thrombotic microangiopathy is relatively poor. Podocyte injury and macrophage infiltration may be involved in the pathogenesis of LN. It may be possible to reverse podocyte damage and decrease the infiltrating macrophages of LN patients through effective treatment.
Publish Date	2024-01-02 09:08
Citation	Liu SY, Chen H, He LJ, Huang CK, Wang P, Rui ZR, Wu J, Yuan Y, Zhang Y, Wang WJ, Wang XD. Changes in macrophage infiltration and podocyte injury in lupus nephritis patients with repeated renal biopsy: Three case reports. World J Clin Cases 2024; 12(1): 188-195
URL	https://www.wjgnet.com/2307-8960/full/v12/i1/188.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i1.188

Full Article (PDF)	WJCC-12-188-with-cover.pdf
Full Article (Word)	WJCC-12-188.docx
CARE Checklist–2016	88717-CARE Checklist (2016).pdf
Manuscript File	88717_Auto_Edited-LJH-YJP_WangTQ.docx
Answering Reviewers	88717-Answering reviewers.pdf
Audio Core Tip	88717-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	88717-Conflict-of-interest statement.pdf
Copyright License Agreement	88717-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	88717-Grant application form(s).pdf
Signed Consent for Treatment Form(s) or Document(s)	88717-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	88717-Language certificate.pdf
Peer-review Report	88717-Peer-review(s).pdf
Scientific Misconduct Check	88717-Bing-Liu JH-2.png
Scientific Misconduct Check	88717-CrossCheck.png
Scientific Editor Work List	88717-Scientific editor work list.pdf
CrossCheck Report	88717-CrossCheck report.pdf