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2/20/2024 12:33:35 PM | Browse: 164 | Download: 495
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Received |
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2023-10-26 09:20 |
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Peer-Review Started |
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2023-10-26 09:22 |
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To Make the First Decision |
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Return for Revision |
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2023-12-15 08:59 |
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Revised |
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2023-12-21 09:19 |
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Second Decision |
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2024-01-29 02:06 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-01-29 07:28 |
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Articles in Press |
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2024-01-29 07:28 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-02-04 10:22 |
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Publish the Manuscript Online |
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2024-02-20 09:51 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Neurosciences |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Correlative factors of poor prognosis and abnormal cellular immune function in patients with Alzheimer’s disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hua Bai, Hong-Mei Zeng, Qi-Fang Zhang, Yue-Zhi Hu and Fei-Fei Deng |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
32060182 and 3206080019 |
| The grant of Science and Technology Support Plan of Guizhou Province in China |
No. [2020]4Y129 |
| Qiannan Prefecture Science and Technology Plan Project in China |
No. [2022]01 |
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| Corresponding Author |
Hua Bai, MD, PhD, Full Professor, Department of Neurology, The Third Affiliated Hospital of Guizhou Medical University in China, No. 172 JianJiangbei Road, Duyun 558099, Guizhou Province, China. baih2020@gmc.edu.cn |
| Key Words |
Alzheimer’s disease; Cellular immunity; Prognosis; T lymphocytes; Magnetic resonance spectroscopy |
| Core Tip |
Abnormal cellular immune function, extrapyramidal symptoms, abnormal electroencephalogram, increased neutrophils and lymphocyte ratio, abnormal magnetic spectroscopy, and complicated pneumonia were related to the poor prognosis of Alzheimer’s disease (AD) patients. The decrease in the proportion of T lymphocytes in the blood after abnormal cellular immune function was an independent risk factor for predicting the poor prognosis of AD. The number of days of donepezil treatment to improve cognitive function was negatively correlated with modified Rankin scale score. The decrease in the proportion of T lymphocytes may have predictive value for the poor prognosis of AD. |
| Publish Date |
2024-02-20 09:51 |
| Citation |
Bai H, Zeng HM, Zhang QF, Hu YZ, Deng FF. Correlative factors of poor prognosis and abnormal cellular immune function in patients with Alzheimer’s disease. World J Clin Cases 2024; 12(6): 1063-1075 |
| URL |
https://www.wjgnet.com/2307-8960/full/v12/i6/1063.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v12.i6.1063 |
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