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5/29/2024 3:09:55 PM | Browse: 183 | Download: 431
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Received |
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2023-12-11 20:53 |
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Peer-Review Started |
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2023-12-11 20:53 |
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To Make the First Decision |
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Return for Revision |
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2024-03-06 21:51 |
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Revised |
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2024-03-19 04:20 |
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Second Decision |
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2024-04-19 02:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-04-19 08:17 |
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Articles in Press |
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2024-04-19 08:17 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-05-27 15:42 |
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Publish the Manuscript Online |
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2024-05-29 12:34 |
ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Infectious Diseases |
Manuscript Type |
Editorial |
Article Title |
Antifungal pipeline: Is there light at the end of the tunnel?
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Manuscript Source |
Invited Manuscript |
All Author List |
Georgios Schinas, Nikolaos Spernovasilis and Karolina Akinosoglou |
Funding Agency and Grant Number |
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Corresponding Author |
Nikolaos Spernovasilis, BSc, MD, MSc, PhD, Director, Director, Department of Infectious Diseases, German Oncology Center, Limassol 4108, Cyprus. nikspe@hotmail.com |
Key Words |
Antifungals; Resistance; Fosmanogepix; Ibrexafungerp; Olorofim |
Core Tip |
The landscape of antifungal therapy has long been dominated by a handful of drug classes, namely azoles, polyenes, and echinocandins. Issues such as the development of resistance/tolerance, interactions and inherent toxicity, and a narrow spectrum of activity have limited their therapeutic utility to clinicians. All these limitations underline the urgent need for novel approaches, with the pipeline for new antifungals having been relatively dry for about 30 years. Thankfully, the pharmaceutical landscape has recently shown promising signs of innovation regarding antifungal agents. |
Publish Date |
2024-05-29 12:34 |
Citation |
<p>Schinas G, Spernovasilis N, Akinosoglou K. Antifungal pipeline: Is there light at the end of the tunnel? <i>World J Clin Cases</i> 2024; 12(16): 2686-2691</p> |
URL |
https://www.wjgnet.com/2307-8960/full/v12/i16/2686.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v12.i16.2686 |
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