Publication Name	World Journal of Cardiology
Manuscript ID	90731
Country	Croatia

Received	2023-12-13 09:06
Peer-Review Started	2023-12-13 09:06
To Make the First Decision
Return for Revision	2024-01-15 09:33
Revised	2024-01-26 17:13
Second Decision	2024-03-04 02:52
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-03-04 07:11
Articles in Press	2024-03-04 07:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-04-17 00:51
Publish the Manuscript Online	2024-04-23 08:34

ISSN	1949-8462 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Biochemistry & Molecular Biology
Manuscript Type	Editorial
Article Title	Hypoxia-inducible factor-1α in myocardial infarction
Manuscript Source	Invited Manuscript
All Author List	Ivana Škrlec and Sergey N Kolomeichuk
Funding Agency and Grant Number	Funding Agency Grant Number Croatian Ministry of Science and Education, Josip Juraj Strossmayer University of Osijek, Faculty of Dental Medicine and Health, Osijek, Croatia IP7-FDMZ-2023 West-Siberian Science and Education Center, Government of Tyumen District, Decree of 20.11.2020 928-rp Ministry of Science and Higher Education FMEN 2022-0009
Corresponding Author	Ivana Škrlec, MSc, PhD, Assistant Professor, Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University of Osijek, Crkvena 21, Osijek 31000, Croatia. iskrlec@fdmz.hr
Key Words	Cardiovascular pathologies; Circadian genes; Hypoxia-inducible factor 1; Hypoxia; Gene-gene interaction
Core Tip	Hypoxia-inducible factor 1 (HIF1), a versatile transcription factor, is crucial for the maintenance of oxygen homeostasis. Genetic variations in HIF1α may influence tissue response to hypoxia and affect clinical manifestations of coronary atherosclerosis. Research has confirmed that sufficient HIF1α expression leads to reperfusion in the ischemic skeletal muscle, whereas decreased expression is associated with hypoxic skin wounds in diabetic animal models. In addition, the HIF1α response can be influenced by circadian proteins. Interpretation of circadian and hypoxia signaling pathways may enable therapeutic interventions in diseases associated with oxygen deprivation, including myocardial infarction.
Publish Date	2024-04-23 08:34
Citation	Škrlec I, Kolomeichuk SN. Hypoxia-inducible factor-1α in myocardial infarction. World J Cardiol 2024; 16(4): 181-185
URL	https://www.wjgnet.com/1949-8462/full/v16/i4/181.htm
DOI	https://dx.doi.org/10.4330/wjc.v16.i4.181

Full Article (PDF)	WJC-16-181-with-cover.pdf
Manuscript File	90731_Auto_Edited-YJP.doc
Answering Reviewers	90731-Answering reviewers.pdf
Audio Core Tip	90731-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	90731-Conflict-of-interest statement.pdf
Copyright License Agreement	90731-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	90731-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	90731-Language certificate.pdf
Peer-review Report	90731-Peer-review(s).pdf
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Scientific Misconduct Check	90731-Bing-Gong ZM-2.png
Scientific Editor Work List	90731-Scientific editor work list.pdf