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3/25/2024 10:04:03 AM | Browse: 92 | Download: 176
Publication Name World Journal of Clinical Cases
Manuscript ID 90878
Country China
2023-12-20 10:01
Peer-Review Started
2023-12-20 10:01
To Make the First Decision
Return for Revision
2024-01-08 10:56
2024-01-22 09:41
Second Decision
2024-02-28 02:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2024-02-28 08:21
Articles in Press
2024-02-28 08:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-03-18 06:56
Publish the Manuscript Online
2024-03-25 08:14
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Upadacitinib for refractory ulcerative colitis with primary nonresponse to infliximab and vedolizumab: A case report
Manuscript Source Unsolicited Manuscript
All Author List Xuan Xu, Jing-Wen Jiang, Bing-Yun Lu and Xia-Xi Li
Funding Agency and Grant Number
Funding Agency Grant Number
Shenzhen Science and Technology Program JCYJ20220530154013031
Guangdong Province Health and Health Appropriate Technology Promotion Project 2023385
Guangdong Province Grassroots Science Popularization Action Plan 20240205
Corresponding Author Xia-Xi Li, PhD, Chief Doctor, Department of Gastroenterology, Shenzhen Hospital of Southern Medical University, No. 1333 Xinhu Road, Shenzhen 518100, Guangdong Province, China. xiaxi_li@foxmail.com
Key Words Upadacitinib; Refractory ulcerative colitis; Primary nonresponse; Infliximab; Vedolizumab; Case report
Core Tip Ulcerative colitis (UC) is a major type of inflammatory bowel disease. Many patients do not respond well to the current therapies. We report the case of a patient diagnosed with refractory UC, with primary nonresponse to infliximab and vedolizumab. The patient experienced recurrent symptoms after receiving mesalazine, prednisone, azathioprine, infliximab, and vedolizumab for more than four years. After optimising the upadacitinib treatment, UC remission was achieved. Our report suggests that the small-molecule upadacitinib may be a new treatment option that deserves to be reported and studied.
Publish Date 2024-03-25 08:14
Citation Xu X, Jiang JW, Lu BY, Li XX. Upadacitinib for refractory ulcerative colitis with primary nonresponse to infliximab and vedolizumab: A case report. World J Clin Cases 2024; 12(9): 1685-1690
URL https://www.wjgnet.com/2307-8960/full/v12/i9/1685.htm
DOI https://dx.doi.org/10.12998/wjcc.v12.i9.1685
Full Article (PDF) WJCC-12-1685-with-cover.pdf
CARE Checklist–2016 90878-CARE Checklist (2016).pdf
Manuscript File 90878_Auto_Edited-YJP.docx
Answering Reviewers 90878-Answering reviewers.pdf
Audio Core Tip 90878-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 90878-Conflict-of-interest statement.pdf
Copyright License Agreement 90878-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 90878-Grant application form(s).pdf
Signed Consent for Treatment Form(s) or Document(s) 90878-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 90878-Language certificate.pdf
Peer-review Report 90878-Peer-review(s).pdf
Scientific Misconduct Check 90878-Bing-Zhang L-2.png
Scientific Editor Work List 90878-Scientific editor work list.pdf