Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	90986
Country	Italy

Received	2023-12-19 08:41
Peer-Review Started	2023-12-19 08:41
To Make the First Decision
Return for Revision	2024-01-15 09:39
Revised	2024-01-15 13:06
Second Decision	2024-02-08 04:45
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-02-08 07:29
Articles in Press	2024-02-08 07:29
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-03-14 01:48
Publish the Manuscript Online	2024-03-22 11:13

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Surgery
Manuscript Type	Editorial
Article Title	Indocyanine green: The guide to safer and more effective surgery
Manuscript Source	Invited Manuscript
All Author List	Pietro Fransvea, Maria Michela Chiarello, Valeria Fico, Maria Cariati and Giuseppe Brisinda
Funding Agency and Grant Number
Corresponding Author	Giuseppe Brisinda, MD, Professor, Surgeon, Department of Abdominal and Endocrine Metabolic Medical and Surgical Sciences, Fondazione Policlinico Universitario A Gemelli IRCCS, No. 8 Largo Agostino Gemelli, Rome 00168, Italy. gbrisin@tin.it
Key Words	Indocyanine green; Colorectal surgery; Fluorescence-guided surgery; Gastrointestinal surgery; Hepato-biliary surgery; Pancreatic surgery; Surgical oncology
Core Tip	Indocyanine green is a sterile, anionic, water-soluble molecule, which was approved for clinical use in 1959 by the Food and Drug Administration. After intravenous injection, indocyanine green rapidly bounds to plasma lipoproteins. When injected outside blood vessels (e.g., into the normal tissue close to tumors), indocyanine green binds to proteins, reaching the nearest lymph node usually within 15 min. The intraoperative usage of indocyanine green has become common in a variety of surgical specialties and transplant surgery. By observing the signal using a fluorescence imaging video system, surgeons can visualize and assess organ perfusion intraoperatively while making adjustments in real-time.
Publish Date	2024-03-22 11:13
Citation	Fransvea P, Chiarello MM, Fico V, Cariati M, Brisinda G. Indocyanine green: The guide to safer and more effective surgery. World J Gastrointest Surg 2024; 16(3): 641-649
URL	https://www.wjgnet.com/1948-9366/full/v16/i3/641.htm
DOI	https://dx.doi.org/10.4240/wjgs.v16.i3.641

Full Article (PDF)	WJGS-16-641-with-cover.pdf
Manuscript File	90986_Auto_Edited-JLW.docx
Answering Reviewers	90986-Answering reviewers.pdf
Audio Core Tip	90986-Audio core tip.aac
Conflict-of-Interest Disclosure Form	90986-Conflict-of-interest statement.pdf
Copyright License Agreement	90986-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	90986-Language certificate.pdf
Peer-review Report	90986-Peer-review(s).pdf
Scientific Misconduct Check	90986-Bing-Lin C-2.png
Scientific Editor Work List	90986-Scientific editor work list.pdf