| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Minireviews |
| Article Title |
Adipose-derived stem cells in diabetic foot care: Bridging clinical trials and practical application
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Song-Lu Tseng, Lin Kang, Zhu-jun Li, Li-Quan Wang, Zi-Ming Li, Tian-Hao Li, Jie-Yu Xiang, Jiu-Zuo Huang, Nan-Ze Yu and Xiao Long |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Key R&D Program of China |
2020YFE0201600 |
| CAMS Innovation Fund for Medical Sciences |
2020-I2M- C&T-A-004 |
| National High Level Hospital Clinical Research Funding |
2022-PUMCH-B-041 and 2022-PUMCH-A-210 |
| National High-Level Hospital Clinical Research Funding |
2022-PUMCH-C-025 |
|
| Corresponding Author |
Xiao Long, MD, PhD, Chief Physician, Department of Plastic and Reconstructive Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Wangfujing, Dongcheng District, Beijing 100730, China. pumclongxiao@126.com |
| Key Words |
Adipose-derived stem cells; Diabetic foot ulcers; Wound healing; Clinical trials; Stem cell therapy; Wound care |
| Core Tip |
This review critically analyzes the current state of research on the efficacy of adipose-derived stem cells (ADSCs) against diabetic foot ulcers (DFUs). It offers a comprehensive overview of diabetic foot classification, clinical management, and the ADSC therapy intricacies. Despite its potential, the field faces challenges like biased trial designs, ambiguous inclusion criteria and intervention strategies. The review highlights these issues and discusses the preclinical efforts to enhance ADSC efficacy. It emphasizes the necessity of more rigorous research and refinement of therapeutic approaches to improve treatment outcomes in diabetic wound care and guide future research. |
| Publish Date |
2024-06-11 14:35 |
| Citation |
<p>Tseng SL, Kang L, Li ZJ, Wang LQ, Li ZM, Li TH, Xiang JY, Huang JZ, Yu NZ, Long X. Adipose-derived stem cells in diabetic foot care: Bridging clinical trials and practical application. <i>World J Diabetes</i> 2024; 15(6): 1162-1177</p> |
| URL |
https://www.wjgnet.com/1948-9358/full/v15/i6/1162.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v15.i6.1162 |
