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1/21/2025 9:38:16 AM | Browse: 453 | Download: 1231
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Received |
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2024-01-12 02:49 |
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Peer-Review Started |
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2024-01-12 02:49 |
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First Decision by Editorial Office Director |
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2024-09-17 21:13 |
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Return for Revision |
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2024-09-17 21:13 |
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Revised |
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2024-11-10 10:31 |
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Publication Fee Transferred |
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2024-11-18 10:30 |
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Second Decision by Editor |
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2024-12-11 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-12-11 08:33 |
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Articles in Press |
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2024-12-11 08:33 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-12-31 15:53 |
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Publish the Manuscript Online |
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2025-01-21 09:26 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Basic Study |
| Article Title |
LEF1 influences diabetic retinopathy and retinal pigment epithelial cell ferroptosis via the miR-495-3p/GRP78 axis through lnc-MGC
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yi-Yi Luo, Xue-Ying Ba, Ling Wang, Ye-Pin Zhang, Hong Xu, Pei-Qi Chen, Li-Bo Zhang, Jian Han and Heng Luo |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Science and Technology Program of Yunnan Provincial Department of Science and Technology-Basic Research Program |
202301BA070001-025 |
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| Corresponding Author |
Heng Luo, MD, Department of Ophthalmology, The People's Hospital of ChuXiong Yi Autonomous Prefecture & The Fourth Affiliated Hospital of DaLi University, No. 318 Lucheng South Road, Chuxiong 675000, China. lh18987837533@163.com |
| Key Words |
Diabetic retinopathy; Endoplasmic reticulum stress; miR-495-3p/GRP78; Lnc-MGC; Retinal pigment epithelium cells; Ferroptosis |
| Core Tip |
Inhibiting lnc-MGC protects Retinal pigment epithelium cells from high glucose-induced apoptosis, inflammation and oxidative stress. Lnc-MGC targeted miR-495-3p and miR-495-3p targeted GRP78. Lnc-MGC regulated ER stress and ferroptosis via miR-495-3p/ GRP78. LEF1 regulated diabetic retinopathy as binding protein of lnc-MGC. |
| Publish Date |
2025-01-21 09:26 |
| Citation |
Luo YY, Ba XY, Wang L, Zhang YP, Xu H, Chen PQ, Zhang LB, Han J, Luo H. LEF1 influences diabetic retinopathy and retinal pigment epithelial cell ferroptosis via the miR-495-3p/GRP78 axis through lnc-MGC. World J Diabetes 2025; 16(3): 92003
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| URL |
https://www.wjgnet.com/1948-9358/full/v16/i3/92003.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i3.92003 |
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