Publication Name	World Journal of Diabetes
Manuscript ID	92003
Country	China

Received	2024-01-12 02:49
Peer-Review Started	2024-01-12 02:49
To Make the First Decision
Return for Revision	2024-09-17 21:13
Revised	2024-11-10 10:31
Second Decision	2024-12-11 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-11 08:33
Articles in Press	2024-12-11 08:33
Publication Fee Transferred	2024-11-18 10:30
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-12-31 15:53
Publish the Manuscript Online	2025-01-21 09:26

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Medicine, Research & Experimental
Manuscript Type	Basic Study
Article Title	LEF1 influences diabetic retinopathy and retinal pigment epithelial cell ferroptosis via the miR-495-3p/GRP78 axis through lnc-MGC
Manuscript Source	Unsolicited Manuscript
All Author List	Yi-Yi Luo, Xue-Ying Ba, Ling Wang, Ye-Pin Zhang, Hong Xu, Pei-Qi Chen, Li-Bo Zhang, Jian Han and Heng Luo
Funding Agency and Grant Number	Funding Agency Grant Number Science and Technology Program of Yunnan Provincial Department of Science and Technology-Basic Research Program 202301BA070001-025
Corresponding Author	Heng Luo, MD, Department of Ophthalmology, The People's Hospital of ChuXiong Yi Autonomous Prefecture & The Fourth Affiliated Hospital of DaLi University, No. 318 Lucheng South Road, Chuxiong 675000, China. lh18987837533@163.com
Key Words	Diabetic retinopathy; Endoplasmic reticulum stress; miR-495-3p/GRP78; Lnc-MGC; Retinal pigment epithelium cells; Ferroptosis
Core Tip	Inhibiting lnc-MGC protects Retinal pigment epithelium cells from high glucose-induced apoptosis, inflammation and oxidative stress. Lnc-MGC targeted miR-495-3p and miR-495-3p targeted GRP78. Lnc-MGC regulated ER stress and ferroptosis via miR-495-3p/ GRP78. LEF1 regulated diabetic retinopathy as binding protein of lnc-MGC.
Publish Date	2025-01-21 09:26
Citation	<p>Luo YY, Ba XY, Wang L, Zhang YP, Xu H, Chen PQ, Zhang LB, Han J, Luo H. LEF1 influences diabetic retinopathy and retinal pigment epithelial cell ferroptosis via the miR-495-3p/GRP78 axis through lnc-MGC. <i>World J Diabetes</i> 2025; 16(3): 92003</p>
URL	https://www.wjgnet.com/1948-9358/full/v16/i3/92003.htm
DOI	https://dx.doi.org/10.4239/wjd.v16.i3.92003

Full Article (PDF)	WJD-16-92003-with-cover.pdf
The ARRIVE Guidelines	92003-The-ARRIVE-Guidelines.pdf
Manuscript File	92003_Auto_Edited_003907.docx
Answering Reviewers	92003-answering-reviewers.pdf
Audio Core Tip	92003-audio.wav
Biostatistics Review Certificate	92003-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	92003-conflict-of-interest-statement.pdf
Copyright License Agreement	92003-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	92003-foundation-statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	92003-institutional-animal-care-and-use-committee-statement.PDF
Non-Native Speakers of English Editing Certificate	92003-non-native-speakers.pdf
Peer-review Report	92003-peer-reviews.pdf
Scientific Misconduct Check	92003-scientific-misconduct-check.png
Scientific Editor Work List	92003-scientific-editor-work-list.pdf
CrossCheck Report	92003-crosscheck-report.png
CrossCheck Report	92003-crosscheck-report.pdf