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6/20/2024 8:20:02 AM | Browse: 184 | Download: 400
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Received |
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2024-01-25 15:13 |
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Peer-Review Started |
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2024-01-25 15:13 |
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To Make the First Decision |
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Return for Revision |
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2024-04-29 20:00 |
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2024-05-10 17:02 |
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Second Decision |
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2024-05-14 02:36 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-05-14 03:50 |
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Articles in Press |
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2024-05-14 03:50 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-05-31 08:54 |
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Publish the Manuscript Online |
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2024-06-20 03:42 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Genetics & Heredity |
| Manuscript Type |
Case Report |
| Article Title |
Successful treatment of severe hepatic impairment in erythropoietic protoporphyria: A case report and review of literature
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Tao Zeng, Shu-Ru Chen, Hao-Qiang Liu, Yu-Tian Chong and Xin-Hua Li |
| Funding Agency and Grant Number |
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| Corresponding Author |
Xin-Hua Li, MD, PhD, Professor, Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Tianhe District, Guangzhou 510630, Guangdong Province, China. lixinh8@mail.sysu.edu.cn |
| Key Words |
Erythropoietic protoporphyria; Red blood cell exchange; Plasma exchange; Delta-aminolevulinic acid; Ferrochelatase; Case report |
| Core Tip |
Erythropoietic protoporphyria (EPP) is a rare autosomal recessive disorder, with few reported cases of associated hepatic injury, posing significant diagnostic challenges. Conventional therapies frequently fall short in severe cases, leading to the necessity for liver transplantation. Here, we report the case of a 35-year-old patient with EPP experiencing progressive liver dysfunction, unresponsive to standard medical care. A novel intervention comprising combined red blood cell exchange and plasma exchange therapies was administered. This approach resulted in a marked improvement in the patient’s liver function, highlighting a potentially effective alternative treatment for serious hepatic manifestations in EPP. |
| Publish Date |
2024-06-20 03:42 |
| Citation |
<p>Zeng T, Chen SR, Liu HQ, Chong YT, Li XH. Successful treatment of severe hepatic impairment in erythropoietic protoporphyria: A case report and review of literature. <i>World J Hepatol</i> 2024; 16(6): 966-972</p> |
| URL |
https://www.wjgnet.com/1948-5182/full/v16/i6/966.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v16.i6.966 |
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