| ISSN |
2220-3141(online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Editorial |
| Article Title |
Extracorporeal organ support for critically ill patients: Overcoming the past, achieving the maximum at present, and redefining the future
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Panagiotis Papamichalis, Katerina G Oikonomou, Maria Xanthoudaki, Asimina Valsamaki, Apostolia-Lemonia Skoura, Sophia K Papathanasiou and Achilleas Chovas |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Panagiotis Papamichalis, MD, PhD, Consultant Physician-Scientist, Intensive Care Unit, General Hospital of Larissa, 1 Tsakalof, Larissa 41221, Greece. ppapamih@med.uth.gr |
| Key Words |
Kidney-liver replacement therapy; Heart-lung support; Blood purification; Native–artificial organ crosstalk; Multiple organ support therapy; Extracorporeal organ support |
| Core Tip |
Supportive therapy remains the cornerstone of care for critically ill patients. Nowadays, extracorporeal organ support (ECOS) systems have made remarkable technological progress and have become widely available in almost every intensive care unit around the world. Long-lasting multiple organ support therapy is feasible for the kidneys, liver, heart, and lungs, while the use of ECOS systems for suppression of various hyperinflammatory conditions, such as sepsis and coronavirus disease 2019, during cardiac surgery, and after cardiac arrest, is an emerging and rapidly recognized indication. Nowadays, combinations of supportive strategies have been developed tailored to the needs of each patient, leading to new ways of understanding and managing multiple organ failure. Moreover, the crosstalk between native and artificial organs is a novel concept that must be further studied, while further research is needed to clarify the indications, therapeutic protocols, and groups of patients suitable for such therapies. |
| Publish Date |
2024-06-03 10:23 |
| Citation |
<p>Papamichalis P, Oikonomou KG, Xanthoudaki M, Valsamaki A, Skoura AL, Papathanasiou SK, Chovas A. Extracorporeal organ support for critically ill patients: Overcoming the past, achieving the maximum at present, and redefining the future. <i>World J Crit Care Med</i> 2024; 13(2): 92458</p> |
| URL |
https://www.wjgnet.com/2220-3141/full/v13/i2/92458.htm |
| DOI |
https://dx.doi.org/10.5492/wjccm.v13.i2.92458 |
