Publication Name	World Journal of Gastroenterology
Manuscript ID	92500
Country	United Kingdom

Received	2024-01-28 00:21
Peer-Review Started	2024-01-28 00:21
To Make the First Decision
Return for Revision	2024-06-18 05:29
Revised	2024-07-04 22:10
Second Decision	2024-09-20 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-09-20 06:19
Articles in Press	2024-09-20 06:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-09-26 01:16
Publish the Manuscript Online	2024-09-29 09:24

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Survival outcomes in early-onset oesophageal adenocarcinoma patients: A systematic review and meta-analyses
Manuscript Source	Invited Manuscript
All Author List	Ashleigh Russell, Shauna Mitchell, Richard C Turkington and Helen G Coleman
Funding Agency and Grant Number
Corresponding Author	Ashleigh Russell, MBChB, MRCP, PhD, Academic Fellow, Staff Physician, Centre for Public Health, Queen's University Belfast, ICS-B Building, Royal Victoria Hospital Site, Grosvenor Road, Belfast BT12 6BA, United Kingdom. a.russell@qub.ac.uk
Key Words	Early-onset cancer; Early-onset oesophageal adenocarcinoma; Survival; Cancer epidemiology; Systematic review; Meta-analysis
Core Tip	In this systematic review, we investigated survival outcomes in early-onset oesophageal adenocarcinoma (OAC) (< 50 years) compared to older age groups. Eleven studies were included. A narrative review of median and mean survival demonstrated conflicting results. Meta-analyses of 5-year survival and risk of death demonstrated no significant difference in survival between younger and older OAC patients. Current evidence in this area has limitations, and up-to-date population-based research is required.
Publish Date	2024-09-29 09:24
Citation	<p>Russell A, Mitchell S, Turkington RC, Coleman HG. Survival outcomes in early-onset oesophageal adenocarcinoma patients: A systematic review and meta-analyses. <i>World J Gastroenterol</i> 2024; 30(38): 4221-4231</p>
URL	https://www.wjgnet.com/1007-9327/full/v30/i38/4221.htm
DOI	https://dx.doi.org/10.3748/wjg.v30.i38.4221

Full Article (PDF)	WJG-30-4221-with-cover.pdf
PRISMA 2009 Checklist	92500-PRISMA-2009-Checklist.pdf
Manuscript File	92500_Auto_Edited_013837.docx
Answering Reviewers	92500-answering-reviewers.pdf
Audio Core Tip	92500-audio.mp3
Biostatistics Review Certificate	92500-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	92500-conflict-of-interest-statement.pdf
Copyright License Agreement	92500-copyright-assignment.pdf
Supplementary Material	92500-supplementary-material.pdf
Peer-review Report	92500-peer-reviews.pdf
Scientific Misconduct Check	92500-scientific-misconduct-check.png
Scientific Editor Work List	92500-scientific-editor-work-list.pdf
CrossCheck Report	92500-crosscheck-report.png
CrossCheck Report	92500-crosscheck-report.pdf