Publication Name	World Journal of Gastroenterology
Manuscript ID	92642
Country	United Kingdom

Received	2024-01-31 18:46
Peer-Review Started	2024-01-31 18:46
To Make the First Decision
Return for Revision	2024-02-08 00:33
Revised	2024-02-23 13:34
Second Decision	2024-03-13 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-03-13 07:03
Articles in Press	2024-03-13 07:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-03-28 01:57
Publish the Manuscript Online	2024-04-03 07:21

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Hepatolithiasis: Epidemiology, presentation, classification and management of a complex disease
Manuscript Source	Invited Manuscript
All Author List	Rodrigo V Motta, Francesca Saffioti and Vasileios K Mavroeidis
Funding Agency and Grant Number
Corresponding Author	Vasileios K Mavroeidis, FACS, FICS, FRCS, MD, MSc, Academic Research, Surgeon, Department of HPB Surgery, Bristol Royal Infirmary, University Hospitals Bristol and Weston NHS Foundation Trust, Upper Maudlin St, Bristol BS2 8HW, United Kingdom. vasileios.mavroeidis@nhs.net
Key Words	Cholelithiasis; Intrahepatic stones; Cholangiocarcinoma; Biliary parasites; Recurrent pyogenic cholangitis; Oriental cholangiohepatitis; Hepatectomy; Cholangioscopy; Liver transplant; Paediatric
Core Tip	Hepatolithiasis is a chronic disease, mostly prevalent in Asia, commonly characterised by recurrent episodes of cholangitis and relevant clinicopathological syndromes, while it constitutes a risk factor for development of intrahepatic cholangiocarcinoma. Its management in complex cases can be challenging and relies upon multidisciplinary input from hepatologists, endoscopists, interventional radiologists and hepatobiliary surgeons. This comprehensive review provides insight on various aspects of hepatolithiasis, with a main focus on the epidemiology, new evidence on pathophysiology, most important clinical aspects, different classification systems and contemporary management.
Publish Date	2024-04-03 07:21
Citation	Motta RV, Saffioti F, Mavroeidis VK. Hepatolithiasis: Epidemiology, presentation, classification and management of a complex disease. World J Gastroenterol 2024; 30(13): 1836-1850
URL	https://www.wjgnet.com/1007-9327/full/v30/i13/1836.htm
DOI	https://dx.doi.org/10.3748/wjg.v30.i13.1836

Full Article (PDF)	WJG-30-1836-with-cover.pdf
Manuscript File	92642_Auto_Edited-YJP.docx
Answering Reviewers	92642-Answering reviewers.pdf
Audio Core Tip	92642-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	92642-Conflict-of-interest statement.pdf
Copyright License Agreement	92642-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	92642-Language certificate.pdf
Peer-review Report	92642-Peer-review(s).pdf
Scientific Misconduct Check	92642-Bing-Lin C-2.png
Scientific Editor Work List	92642-Scientific editor work list.pdf
CrossCheck Report	92642-CrossCheck.png
CrossCheck Report	92642-CrossCheck report.pdf