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5/29/2024 3:09:55 PM | Browse: 560 | Download: 1188
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Received |
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2024-02-04 15:45 |
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Peer-Review Started |
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2024-02-04 15:45 |
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First Decision by Editorial Office Director |
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2024-02-29 19:32 |
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2024-02-29 19:32 |
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Revised |
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2024-03-04 12:47 |
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Second Decision by Editor |
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2024-04-10 02:34 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-04-10 06:52 |
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Articles in Press |
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2024-04-10 06:52 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-05-27 15:44 |
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Publish the Manuscript Online |
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2024-05-29 12:34 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Rheumatology |
| Manuscript Type |
Case Report |
| Article Title |
Dynamically changing antineutrophil cytoplasmic antibodies in granulomatosis with polyangiitis: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yan Zhang, Qiao-Ding Dai, Ji-An Wang, Li-Ping Xu, Qiang Chen and Yang-Zi Jin |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Research Project of Zhejiang Chinese Medical University |
2023JKZKTS33 |
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| Corresponding Author |
Yang-Zi Jin, MD, Attending Doctor, Department of Otolaryngology, The First Affiliated Hospital of Zhejiang Chinese Medical University/Zhejiang Provincial Hospital of Traditional Chinese Medicine, No. 54 Youdian Road, Hangzhou 310006, Zhejiang Province, China. 20163249@zcmu.edu.cn |
| Key Words |
Anti-neutrophil cytoplasmic antibodies; Granulomatosis with polyangiitis; Antineutrophil cytoplasmic antibody-associated vasculitis; Immunosuppressive therapy; Case report |
| Core Tip |
In this case, otomastoiditis was the initial clinical manifestation, and then the clinical manifestations of central system involvement gradually appeared. Laboratory examination showed that proteinase 3-antineutrophil cytoplasmic antibody (ANCA) changed from negative to positive 3 months later. Therefore, for patients with clinical suspicion of granulomatosis with polyangiitis (GPA), repeated examination of ANCA should be considered, and obtained pathological evidence whenever possible. Meanwhile, the importance of early participation of the rheumatological immunology team is emphasized. Through multidisciplinary communication, the probability of early diagnosis of GPA can be improved, and timely drug intervention can be carried out to prevent disease progression and reduce the risk of local and systemic sequelae. |
| Publish Date |
2024-05-29 12:34 |
| Citation |
Zhang Y, Dai QD, Wang JA, Xu LP, Chen Q, Jin YZ. Dynamically changing antineutrophil cytoplasmic antibodies in granulomatosis with polyangiitis: A case report. World J Clin Cases 2024; 12(16): 2881-2886
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| URL |
https://www.wjgnet.com/2307-8960/full/v12/i16/2881.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v12.i16.2881 |
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