Publication Name	World Journal of Clinical Cases
Manuscript ID	92667
Country	China

Received	2024-02-04 15:45
Peer-Review Started	2024-02-04 15:45
To Make the First Decision
Return for Revision	2024-02-29 19:32
Revised	2024-03-04 12:47
Second Decision	2024-04-10 02:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-04-10 06:52
Articles in Press	2024-04-10 06:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-27 15:44
Publish the Manuscript Online	2024-05-29 12:34

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Rheumatology
Manuscript Type	Case Report
Article Title	Dynamically changing antineutrophil cytoplasmic antibodies in granulomatosis with polyangiitis: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Yan Zhang, Qiao-Ding Dai, Ji-An Wang, Li-Ping Xu, Qiang Chen and Yang-Zi Jin
Funding Agency and Grant Number	Funding Agency Grant Number The Research Project of Zhejiang Chinese Medical University 2023JKZKTS33
Corresponding Author	Yang-Zi Jin, MD, Attending Doctor, Department of Otolaryngology, The First Affiliated Hospital of Zhejiang Chinese Medical University/Zhejiang Provincial Hospital of Traditional Chinese Medicine, No. 54 Youdian Road, Hangzhou 310006, Zhejiang Province, China. 20163249@zcmu.edu.cn
Key Words	Anti-neutrophil cytoplasmic antibodies; Granulomatosis with polyangiitis; Antineutrophil cytoplasmic antibody-associated vasculitis; Immunosuppressive therapy; Case report
Core Tip	In this case, otomastoiditis was the initial clinical manifestation, and then the clinical manifestations of central system involvement gradually appeared. Laboratory examination showed that proteinase 3-antineutrophil cytoplasmic antibody (ANCA) changed from negative to positive 3 months later. Therefore, for patients with clinical suspicion of granulomatosis with polyangiitis (GPA), repeated examination of ANCA should be considered, and obtained pathological evidence whenever possible. Meanwhile, the importance of early participation of the rheumatological immunology team is emphasized. Through multidisciplinary communication, the probability of early diagnosis of GPA can be improved, and timely drug intervention can be carried out to prevent disease progression and reduce the risk of local and systemic sequelae.
Publish Date	2024-05-29 12:34
Citation	<p>Zhang Y, Dai QD, Wang JA, Xu LP, Chen Q, Jin YZ. Dynamically changing antineutrophil cytoplasmic antibodies in granulomatosis with polyangiitis: A case report. <i>World J Clin Cases</i> 2024; 12(16): 2881-2886</p>
URL	https://www.wjgnet.com/2307-8960/full/v12/i16/2881.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i16.2881

Full Article (PDF)	WJCC-12-2881-with-cover.pdf
CARE Checklist–2016	92667-CARE Checklist (2016).pdf
Manuscript File	92667_Auto_Edited-YJP.docx
Answering Reviewers	92667-Answering reviewers.pdf
Audio Core Tip	92667-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	92667-CARE Checklist (2016).pdf
Copyright License Agreement	92667-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	92667-Grant application form(s).pdf
Signed Consent for Treatment Form(s) or Document(s)	92667-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	92667-Language certificate.pdf
Peer-review Report	92667-Peer-review(s).pdf
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Scientific Misconduct Check	92667-CrossCheck.png
Scientific Editor Work List	92667-Scientific editor work list.pdf
CrossCheck Report	92667-CrossCheck report.pdf