Publication Name	World Journal of Clinical Cases
Manuscript ID	92730
Country	China

Received	2024-02-04 04:34
Peer-Review Started	2024-02-04 04:34
To Make the First Decision
Return for Revision	2024-03-06 21:23
Revised	2024-03-08 11:09
Second Decision	2024-04-09 03:14
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-04-09 08:31
Articles in Press	2024-04-09 08:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-08 06:57
Publish the Manuscript Online	2024-05-14 08:48

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Case Report
Article Title	Tuberous sclerosis complex combined with primary lymphedema: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Xing-Peng Li, Xiao-Li Sun, Xin Liu, Zhe Wen, Li-Hua Jiang, Yan Fu, Yun-Long Yue and Ren-Gui Wang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 61876216
Corresponding Author	Ren-Gui Wang, MD, PhD, Chief Doctor, Chief Physician, Full Professor, Department of Radiology, Beijing Shijitan Hospital Affiliated to Capital Medical University, No. 10 Yangfangdian Tieyi Road, Beijing 100038, China. wangrg@bjsjth.cn
Key Words	Tuberous sclerosis complex; Lymphedema; Sirolimus; Multimodal imaging examination; Case report
Core Tip	Tuberous sclerosis complex with primary lymphedema (TSC-PLE) is a rare, congenital and systemic disease closely related to gene mutations. The clinical manifestations of TSC-PLE are diverse. Multiple imaging methods can detect systemic organ and tissue lesions, which are important for clinical diagnosis and treatment. Rapamycin-targeted therapy is the main treatment for this disease and can simultaneously treat the symptoms of both TSC and PLE. Liposuction can effectively improve limb swelling in patients. This case is the 17th patient with TSC-PLE worldwide. And this case has comprehensive clinical, imaging, genetic testing and treatment.
Publish Date	2024-05-14 08:48
Citation	<p>Li XP, Sun XL, Liu X, Wen Z, Jiang LH, Fu Y, Yue YL, Wang RG. Tuberous sclerosis complex combined with primary lymphedema: A case report. <i>World J Clin Cases</i> 2024; 12(15): 2642-2648</p>
URL	https://www.wjgnet.com/2307-8960/full/v12/i15/2642.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i15.2642

Full Article (PDF)	WJCC-12-2642-with-cover.pdf
CARE Checklist–2016	92730-CARE Checklist (2016).pdf
Manuscript File	92730_Auto_Edited-YJP.docx
Answering Reviewers	92730-Answering reviewers.pdf
Audio Core Tip	92730-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	92730-Conflict-of-interest statement.pdf
Copyright License Agreement	92730-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	92730-Grant application form(s).pdf
Signed Consent for Treatment Form(s) or Document(s)	92730-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	92730-Language certificate.pdf
Peer-review Report	92730-Peer-review(s).pdf
Scientific Misconduct Check	92730-Bing-Zheng XM-2.png
Scientific Misconduct Check	92730-CrossCheck.png
Scientific Editor Work List	92730-Scientific editor work list.pdf
CrossCheck Report	92730-CrossCheck report.pdf