Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	93201
Country	United States

Received	2024-02-21 15:17
Peer-Review Started	2024-02-21 15:17
To Make the First Decision
Return for Revision	2024-04-17 08:08
Revised	2024-04-18 13:39
Second Decision	2024-04-23 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-04-23 06:55
Articles in Press	2024-04-23 06:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-06-14 12:14
Publish the Manuscript Online	2024-06-30 07:39

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Surgery
Manuscript Type	Editorial
Article Title	Non-operative management of rectal cancer: Highlighting the controversies
Manuscript Source	Invited Manuscript
All Author List	Sameh Hany Emile and Anjelli Wignakumar
Funding Agency and Grant Number
Corresponding Author	Sameh Hany Emile, FACS, MD, MSc, PhD, Associate Professor, Research Scientist, Surgeon, Department of Colorectal Surgery, Cleveland Clinic Florida, No. 2950 Cleveland Clinic Blvd, Weston, FL 33331, United States. sameh200@hotmail.com
Key Words	Non-operative; Management; Rectal cancer; Highlighting; Controversies
Core Tip	Patients with locally advanced rectal cancers are ideally treated with neoadjuvant chemoradiation therapy followed by surgical resection. As neoadjuvant treatments evolved, an increasing number of patients showed a complete response to neoadjuvant therapy. The complete response of rectal cancers to neoadjuvant treatment inspired the concept of non-operative management (NOM). Following extensive multidisciplinary team meeting discussion, patients can be considered for NOM. Questions arose regarding patient selection for NOM and the best surveillance program to ensure no red flags for recurrent disease. Another consideration is how patients who develop recurrence be managed.
Publish Date	2024-06-30 07:39
Citation	<p>Emile SH, Wignakumar A. Non-operative management of rectal cancer: Highlighting the controversies. <i>World J Gastrointest Surg</i> 2024; 16(6): 1501-1506</p>
URL	https://www.wjgnet.com/1948-9366/full/v16/i6/1501.htm
DOI	https://dx.doi.org/10.4240/wjgs.v16.i6.1501

Full Article (PDF)	WJGS-16-1501-with-cover.pdf
Manuscript File	93201_Auto_Edited-YJP.docx
Answering Reviewers	93201-answering-reviewers.pdf
Audio Core Tip	93201-audio.m4a
Conflict-of-Interest Disclosure Form	93201-conflict-of-interest-statement.pdf
Copyright License Agreement	93201-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	93201-non-native-speakers.pdf
Peer-review Report	93201-peer-reviews.pdf
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Scientific Editor Work List	93201-scientific-editor-work-list.pdf
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CrossCheck Report	93201-crosscheck-report.pdf