Publication Name	World Journal of Clinical Cases
Manuscript ID	93941
Country	China

Received	2024-03-08 08:53
Peer-Review Started	2024-03-08 08:53
To Make the First Decision
Return for Revision	2024-04-16 21:18
Revised	2024-05-25 12:49
Second Decision	2024-07-01 02:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-07-01 09:32
Articles in Press	2024-07-01 09:32
Publication Fee Transferred	2024-07-06 07:45
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-07-12 02:07
Publish the Manuscript Online	2024-07-17 05:55

ISSN	2307-8960 (online)
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Category	Emergency Medicine
Manuscript Type	Case Control Study
Article Title	Differential expression of plasma cytokines in sepsis patients and their clinical implications
Manuscript Source	Unsolicited Manuscript
All Author List	Hui-Xiu Liu, Yu-Ying Wang and Xue-Feng Yang
Funding Agency and Grant Number	Funding Agency Grant Number The Project of Hengyang Science and Technology Bureau 202222035602
Corresponding Author	Xue-Feng Yang, PhD, Professor, Department of Gastroenterology, The Affiliated Nanhua Hospital, Hengyang Medical School, University of South China, No. 336 Dongfeng South Road, Zhuhui District, Hengyang 421002, Hunan Province, China. yxf9988@126.com
Key Words	Sepsis; Cytokines; Biomarkers; Protein chip; Patients
Core Tip	Clinically, sequential organ failure assessment (SOFA) or quick SOFA (qSOFA) scores are often used to identify and diagnose sepsis. However, some scholars have found that qSOFA scores are not good at predicting severe sepsis and mortality. Therefore, it is necessary to explore a new diagnostic method for sepsis. In this study, changes in plasma cytokine levels in patients with sepsis were assessed. We found that the serum levels of the cytokines interleukin16, granulocyte-macrophage colony-stimulating factor, CX3CL1, CXCL9, CXCL16, CCL25 and CCL23 were significantly increased in patients with sepsis, representing potential diagnostic biomarkers of sepsis.
Publish Date	2024-07-17 05:55
Citation	<p>Liu HX, Wang YY, Yang XF. Differential expression of plasma cytokines in sepsis patients and their clinical implications. <i>World J Clin Cases</i> 2024; 12(25): 5681-5696</p>
URL	https://www.wjgnet.com/2307-8960/full/v12/i25/5681.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i25.5681

Full Article (PDF)	WJCC-12-5681-with-cover.pdf
STROBE Statement	93941-STROBE-statement.pdf
Manuscript File	93941_Auto_Edited_072536.docx
Answering Reviewers	93941-answering-reviewers.pdf
Audio Core Tip	93941-audio.mp4
Biostatistics Review Certificate	93941-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	93941-conflict-of-interest-statement.pdf
Copyright License Agreement	93941-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	93941-foundation-statement.pdf
Signed Informed Consent Form(s) or Document(s)	93941-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	93941-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	93941-non-native-speakers.pdf
Peer-review Report	93941-peer-reviews.pdf
Scientific Misconduct Check	93941-scientific-misconduct-check.png
Scientific Editor Work List	93941-scientific-editor-work-list.pdf
CrossCheck Report	93941-crosscheck-report.pdf
CrossCheck Report	93941-crosscheck-report.png