BPG is committed to discovery and dissemination of knowledge
Featured Articles
1/21/2025 9:40:07 AM | Browse: 306 | Download: 1142
 |
Received |
|
2024-03-11 10:01 |
|
Peer-Review Started |
|
2024-03-11 10:01 |
|
First Decision by Editorial Office Director |
|
2024-09-23 08:49 |
|
Return for Revision |
|
2024-09-23 08:49 |
|
Revised |
|
2024-10-17 09:20 |
|
Publication Fee Transferred |
|
2024-12-02 01:18 |
|
Second Decision by Editor |
|
2024-11-25 02:39 |
 |
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2024-11-25 06:38 |
|
Articles in Press |
|
2024-11-25 06:38 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2025-01-13 01:33 |
|
Publish the Manuscript Online |
|
2025-01-21 09:22 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
Transmembrane channel-like 5 drives hepatocellular carcinoma progression by regulating epithelial-mesenchymal transition
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jiao Li, Zi-Yu Wang, Yan Jin, Jing Xu, Yun-Jin Ya, Ting-Qiu Wan, Xi Li and Xi Wang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Yunnan Provincial Department of Science and Technology-Kunming Medical University Joint Special Project on Applied Basic Research |
202401AY070001-132 |
| the Yunnan Provincial Science Foundation |
2018FE001(-287) |
| National Natural Science Foundation of China |
81460443 |
| the Ten Thousand People Plan of Yunnan Province |
KH-SWR-MY-2020-002 |
|
| Corresponding Author |
Yan Jin, Chief Physician, Department of Hepatobiliary Surgery, The Affiliated Hospital of Kunming University of Science and Technology, No. 157 Jinbi Road，Xishan District, Kunming 650500, Yunnan Province, China. 13312503258@163.com |
| Key Words |
Hepatocellular carcinoma; Transmembrane channel-like protein 5; Epithelial-mesenchymal transition; Bioinformatics; diagnosis; Prognosis |
| Core Tip |
In this study, transmembrane channel-like 5 (TMC5), which is highly expressed in hepatocellular carcinoma (HCC) and associated with increased invasive migration ability, is proposed for the first time as a potential marker for HCC. Bioinformatics analysis and in vivo and in vitro experiments confirmed that TMC5 regulates epithelial-mesenchymal transition to promote invasive migration in HCC. TMC5 might be a valuable molecular target for HCC diagnosis and treatment. |
| Publish Date |
2025-01-21 09:22 |
| Citation |
Li J, Wang ZY, Jin Y, Xu J, Ya YJ, Wan TQ, Li X, Wang X. Transmembrane channel-like 5 drives hepatocellular carcinoma progression by regulating epithelial-mesenchymal transition. World J Clin Oncol 2025; 16(3): 94091 |
| URL |
https://www.wjgnet.com/2218-4333/full/v16/i3/94091.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v16.i3.94091 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
