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1/21/2025 9:40:07 AM | Browse: 65 | Download: 139
Publication Name World Journal of Clinical Oncology
Manuscript ID 94091
Country China
Received
2024-03-11 10:01
Peer-Review Started
2024-03-11 10:01
To Make the First Decision
Return for Revision
2024-09-23 08:49
Revised
2024-10-17 09:20
Second Decision
2024-11-25 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-11-25 06:38
Articles in Press
2024-11-25 06:38
Publication Fee Transferred
2024-12-02 01:18
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-01-13 01:33
Publish the Manuscript Online
2025-01-21 09:22
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Basic Study
Article Title Transmembrane channel-like 5 drives hepatocellular carcinoma progression by regulating epithelial-mesenchymal transition
Manuscript Source Unsolicited Manuscript
All Author List Jiao Li, Zi-Yu Wang, Yan Jin, Jing Xu, Yun-Jin Ya, Ting-Qiu Wan, Xi Li and Xi Wang
Funding Agency and Grant Number
Funding Agency Grant Number
the Yunnan Provincial Department of Science and Technology-Kunming Medical University Joint Special Project on Applied Basic Research 202401AY070001-132
the Yunnan Provincial Science Foundation 2018FE001(-287)
National Natural Science Foundation of China 81460443
the Ten Thousand People Plan of Yunnan Province KH-SWR-MY-2020-002
Corresponding Author Yan Jin, Chief Physician, Department of Hepatobiliary Surgery, The Affiliated Hospital of Kunming University of Science and Technology, No. 157 Jinbi Road,Xishan District, Kunming 650500, Yunnan Province, China. 13312503258@163.com
Key Words Hepatocellular carcinoma; Transmembrane channel-like protein 5; Epithelial-mesenchymal transition; Bioinformatics; diagnosis; Prognosis
Core Tip In this study, transmembrane channel-like 5 (TMC5), which is highly expressed in hepatocellular carcinoma (HCC) and associated with increased invasive migration ability, is proposed for the first time as a potential marker for HCC. Bioinformatics analysis and in vivo and in vitro experiments confirmed that TMC5 regulates epithelial-mesenchymal transition to promote invasive migration in HCC. TMC5 might be a valuable molecular target for HCC diagnosis and treatment.
Publish Date 2025-01-21 09:22
Citation <p>Li J, Wang ZY, Jin Y, Xu J, Ya YJ, Wan TQ, Li X, Wang X. Transmembrane channel-like 5 drives hepatocellular carcinoma progression by regulating epithelial-mesenchymal transition. <i>World J Clin Oncol</i> 2025; 16(3): 94091</p>
URL https://www.wjgnet.com/2218-4333/full/v16/i3/94091.htm
DOI https://dx.doi.org/10.5306/wjco.v16.i3.94091
Full Article (PDF) WJCO-16-94091-with-cover.pdf
The ARRIVE Guidelines 94091-The-ARRIVE-Guidelines.pdf
Manuscript File 94091_Auto_Edited_014714.docx
Answering Reviewers 94091-answering-reviewers.pdf
Audio Core Tip 94091-audio.m4a
Biostatistics Review Certificate 94091-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 94091-conflict-of-interest-statement.pdf
Copyright License Agreement 94091-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 94091-foundation-statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document 94091-institutional-animal-care-and-use-committee-statement.pdf
Institutional Review Board Approval Form or Document 94091-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 94091-non-native-speakers.pdf
Peer-review Report 94091-peer-reviews.pdf
Scientific Misconduct Check 94091-scientific-misconduct-check.png
Scientific Editor Work List 94091-scientific-editor-work-list.pdf
CrossCheck Report 94091-crosscheck-report.png
CrossCheck Report 94091-crosscheck-report.pdf