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10/30/2024 11:04:17 AM | Browse: 12 | Download: 36
Publication Name World Journal of Clinical Pediatrics
Manuscript ID 94156
Country Italy
Received
2024-03-12 13:50
Peer-Review Started
2024-03-12 13:50
To Make the First Decision
Return for Revision
2024-05-24 06:40
Revised
2024-06-06 16:44
Second Decision
2024-07-02 02:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-07-02 10:16
Articles in Press
2024-07-02 10:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-09-30 06:36
Publish the Manuscript Online
2024-10-30 10:50
ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https: //creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pediatrics
Manuscript Type Case Report
Article Title Diazoxide toxicity in congenital hyperinsulinism: A case report
Manuscript Source Unsolicited Manuscript
All Author List Roberta Pajno, Camilla Visconti, Carmen Bucolo, Maria Pia Guarneri, Paolo Del Barba, Paolo Silvani, Marco Gregnanin and Graziano Barera
Funding Agency and Grant Number
Corresponding Author Roberta Pajno, MD, Attending Doctor, Department of Pediatric, Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele Institute, Via Olgettina 60, Milan 20132, Lombardy, Italy. pajno.roberta@hsr.it
Key Words Diazoxide; Hypoglycemia; Congenital hyperinsulinism; Side effect; Case report
Core Tip Diazoxide can be effective in treating congenital hyperinsulinism, but its use requires diuretic administration and careful surveillance to prevent and promptly diagnose potential life-threatening adverse effects. Although diazoxide cardiopulmonary side effects were previously described in sporadic case reports, the United States Food and Drug Administration (FDA) has clearly listed them as severe adverse events since 2015. Despite this, numerous reports were published after the FDA statement, describing the increasing rate of these diazoxide side effects. Further studies are needed to identify the underlying mechanism and precise predisposing factors.
Publish Date 2024-10-30 10:50
Citation <p>Pajno R, Visconti C, Bucolo C, Guarneri MP, Del Barba P, Silvani P, Gregnanin M, Barera G. Diazoxide toxicity in congenital hyperinsulinism: A case report. <i>World J Clin Pediatr</i> 2024; 13(4): 94156</p>
URL https://www.wjgnet.com/2219-2808/full/v13/i4/94156.htm
DOI https://dx.doi.org/10.5409/wjcp.v13.i4.94156
Full Article (PDF) WJCP-13-94156-with-cover.pdf
CARE Checklist–2016 94156-CARE-Checklist-2016.pdf
Manuscript File 94156_Auto_Edited_012734.docx
Answering Reviewers 94156-answering-reviewers.pdf
Audio Core Tip 94156-audio.m4a
Conflict-of-Interest Disclosure Form 94156-conflict-of-interest-statement.pdf
Copyright License Agreement 94156-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 94156-informed-consent-statement.pdf
Peer-review Report 94156-peer-reviews.pdf
Scientific Misconduct Check 94156-scientific-misconduct-check.png
Scientific Editor Work List 94156-scientific-editor-work-list.pdf
CrossCheck Report 94156-crosscheck-report.pdf