Publication Name	World Journal of Hematology
Manuscript ID	94171
Country	Cameroon

Received	2024-03-12 18:16
Peer-Review Started	2024-03-12 18:16
To Make the First Decision
Return for Revision	2024-04-29 23:03
Revised	2024-05-28 08:14
Second Decision	2024-06-20 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-06-20 05:51
Articles in Press	2024-06-20 05:51
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-06-21 15:38
Typeset the Manuscript	2024-06-26 09:16
Publish the Manuscript Online	2024-07-05 03:06

ISSN	2218-6204 (online)
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Category	Biochemistry & Molecular Biology
Manuscript Type	Minireviews
Article Title	Haptoglobin: A protein with little-explored properties? Involvement in the development of diseases
Manuscript Source	Invited Manuscript
All Author List	Romaric Tuono De Manfouo, Josué Simo Louokdom, Bernard Claude Chetcha, Larissa Michelle Bakam Magoua, Prosper Cabral Biapa Nya, Constant Anatole Pieme and Claude Tayou Tagny
Funding Agency and Grant Number
Corresponding Author	Romaric Tuono De Manfouo, MSc, Research Fellow, Department of Microbiology, Parasitology, Hematology, and Infectious Diseases, Hematology Unit, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé 296, Cameroon. romatuono@yahoo.fr
Key Words	Haptoglobin; Protein; Properties; Polymorphism; Diseases
Core Tip	Haptoglobin is a serum glycoprotein of hepatocytic origin synthesized during the acute phases of inflammation. Its synthesis is thought to have pro-inflammatory and anti-inflammatory, pro-oxidative, and antioxidant actions, depending on the genotype of haptoglobin present in the individual. This is how its polymorphism describes 3 main forms haptoglobin (HP) 2-2, HP 2-1, and HP 1-1. Studies have described the association of haptoglobin genotypes 2-2 with worsening of the disease; while genotype 1-1 is more likely to have a protective action. Thus, it would be important to identify and know one's genotype because this would make it possible to prognosticate and prevent certain diseases.
Publish Date	2024-07-05 03:06
Citation	<p>Tuono De Manfouo R, Louokdom JS, Chetcha BC, Bakam Magoua LM, Nya PCB, Pieme CA, Tayou Tagny C. Haptoglobin: A protein with little-explored properties? Involvement in the development of diseases. <i>World J Hematol</i> 2024; 11(2): 94171</p>
URL	https://www.wjgnet.com/2218-6204/full/v11/i2/94171.htm
DOI	https://dx.doi.org/10.5315/wjh.v11.i2.94171

Full Article (PDF)	WJH-11-94171-with-cover.pdf
Manuscript File	94171_Auto_Edited-YJP_Kerr C_Clear Copy.docx
Answering Reviewers	94171-answering-reviewers.pdf
Audio Core Tip	94171-audio.mp3
Conflict-of-Interest Disclosure Form	94171-conflict-of-interest-statement.pdf
Copyright License Agreement	94171-copyright-assignment.pdf
Peer-review Report	94171-peer-reviews.pdf
Scientific Misconduct Check	94171-scientific-misconduct-check.png
Scientific Editor Work List	94171-scientific-editor-work-list.pdf
CrossCheck Report	94171-crosscheck-report.pdf