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7/9/2024 2:26:32 PM | Browse: 39 | Download: 29
Publication Name World Journal of Gastroenterology
Manuscript ID 94441
Country United States
Received
2024-03-18 19:20
Peer-Review Started
2024-03-18 19:20
To Make the First Decision
Return for Revision
2024-05-24 03:59
Revised
2024-06-04 03:59
Second Decision
2024-06-24 02:39
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2024-06-24 06:26
Articles in Press
2024-06-24 06:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-06-28 14:55
Publish the Manuscript Online
2024-07-09 14:00
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Editorial
Article Title Digesting gluten with oral endopeptidases to improve the management of celiac disease
Manuscript Source Invited Manuscript
All Author List Katelin Durham and Mirac Nedim Ince
Funding Agency and Grant Number
Funding Agency Grant Number
VA Merit Award 2I01BX002906-05
Corresponding Author Mirac Nedim Ince, MD, Associate Professor, Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Iowa, Carver College of Medicine, 4546 JCP, 200 Hawkins Drive, Iowa City, IA 52242, United States. m-nedim-ince@uiowa.edu
Key Words Celiac disease; Gluten-free diet; Endopeptidase; Villous atrophy; Aspergillus niger; Adjunct therapy
Core Tip Patients with celiac disease may still be exposed to gluten despite earnest attempts at adhering to a strict gluten-free diet. Gluten-digesting endopeptidases have emerged as an adjunct therapy for celiac disease. Such endopeptidases digest gluten within the gut to prevent its uptake by antigen presenting cells which initiate small bowel inflammation and villous atrophy. The prolyl endopeptidase derived from Aspergillus niger has shown potential to reduce inadvertent dietary gluten exposure and improve patients’ quality of life.
Publish Date 2024-07-09 14:00
Citation <p>Durham K, Ince MN. Digesting gluten with oral endopeptidases to improve the management of celiac disease. <i>World J Gastroenterol</i> 2024; 30(26): 3201-3205</p>
URL https://www.wjgnet.com/1007-9327/full/v30/i26/3201.htm
DOI https://dx.doi.org/10.3748/wjg.v30.i26.3201
Full Article (PDF) WJG-30-3201-with-cover.pdf
Manuscript File 94441_Auto_Edited-YJP.docx
Answering Reviewers 94441-answering-reviewers.pdf
Audio Core Tip 94441-audio.mp3
Conflict-of-Interest Disclosure Form 94441-conflict-of-interest-statement.pdf
Copyright License Agreement 94441-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 94441-foundation-statement.pdf
Peer-review Report 94441-peer-reviews.pdf
Scientific Misconduct Check 94441-scientific-misconduct-check.png
Scientific Editor Work List 94441-scientific-editor-work-list.pdf
CrossCheck Report 94441-crosscheck-report.pdf