Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	94623
Country	China

Received	2024-03-21 11:36
Peer-Review Started	2024-03-21 11:36
To Make the First Decision
Return for Revision	2024-05-15 21:49
Revised	2024-05-27 17:57
Second Decision	2024-08-09 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-08-09 05:48
Articles in Press	2024-08-09 05:48
Publication Fee Transferred	2024-08-10 03:35
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-08-20 02:30
Publish the Manuscript Online	2024-09-09 08:41

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Roles of the tumor microenvironment in the resistance to programmed cell death protein 1 inhibitors in patients with gastric cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Ren-Jie Xia, Xiao-Yu Du, Li-Wen Shen, Jian-Guo Ma, Shu-Mei Xu, Rui-Fang Fan, Jian-Wei Qin and Long Yan
Funding Agency and Grant Number	Funding Agency Grant Number Natural Science Foundation of Gansu Province 21JR1RA186 Health Industry Research Program of Gansu Province GSWSKY2021-043
Corresponding Author	Long Yan, MD, Associate Chief Physician, Department of General Surgery, The 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation Army, No. 333 Nanbinhe Middle Road, Qilihe District, Lanzhou 730050, Gansu Province, China. lzzy940@163.com
Key Words	Gastric cancer; Tumor microenvironment; Programmed cell death protein 1; Immunotherapy; Drug resistance
Core Tip	The discovery of immunotherapy has changed the management of patients with gastric cancer (GC). Programmed cell death protein 1 (PD-1) inhibitors are revolutionary drugs for the therapeutic approach of GC, but resistance to PD-1 inhibitors often occurs in patients with GC. We herein discuss the effects of the tumor microenvironment on the resistance to PD-1 inhibitors in GC patients, aiming to reduce this resistance in the future.
Publish Date	2024-09-09 08:41
Citation	<p>Xia RJ, Du XY, Shen LW, Ma JG, Xu SM, Fan RF, Qin JW, Yan L. Roles of the tumor microenvironment in the resistance to programmed cell death protein 1 inhibitors in patients with gastric cancer. <i>World J Gastrointest Oncol</i> 2024; 16(9): 3820-3831</p>
URL	https://www.wjgnet.com/1948-5204/full/v16/i9/3820.htm
DOI	https://dx.doi.org/10.4251/wjgo.v16.i9.3820

Full Article (PDF)	WJGO-16-3820-with-cover.pdf
Manuscript File	94623_Auto_Edited_005320.docx
Answering Reviewers	94623-answering-reviewers.pdf
Audio Core Tip	94623-audio.m4a
Conflict-of-Interest Disclosure Form	94623-conflict-of-interest-statement.pdf
Copyright License Agreement	94623-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	94623-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	94623-non-native-speakers.pdf
Peer-review Report	94623-peer-reviews.pdf
Scientific Misconduct Check	94623-scientific-misconduct-check.png
Scientific Editor Work List	94623-scientific-editor-work-list.pdf
CrossCheck Report	94623-crosscheck-report.pdf