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7/12/2024 5:20:14 PM | Browse: 280 | Download: 406
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Received |
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2024-03-23 08:09 |
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Peer-Review Started |
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2024-03-23 08:09 |
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To Make the First Decision |
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Return for Revision |
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2024-05-01 20:05 |
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Revised |
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2024-05-14 16:45 |
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Second Decision |
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2024-06-04 02:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-06-04 06:36 |
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Articles in Press |
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2024-06-04 06:36 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2024-06-10 14:12 |
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Typeset the Manuscript |
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2024-06-17 06:22 |
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Publish the Manuscript Online |
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2024-07-12 15:55 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
CNPY3 is a prognostic factor in colon adenocarcinoma which is associated with immune infiltration and affects the PI3K/AKT pathway
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xu-Can Gao, Biao-Huan Zhou, Zhou-Xin Ji, Qiang Li and Hui-Ning Liu |
| Funding Agency and Grant Number |
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| Corresponding Author |
Xu-Can Gao, MD, Doctor, Doctor, Department of Anorectal Surgery, Shenzhen People’s Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), No. 1017 Dongmen North Road, Cuizhu Street, Luohu District, Shenzhen 518020, Guangdong Province, China. logia@szhospital.com |
| Key Words |
Canopy FGF signaling regulator 3; Colon cancer; Biomarker; Immune infiltration; Prognosis |
| Core Tip |
First, this is the first study that reported CNPY3 was up-regulated in colon adenocarcinoma and might regulate tumor development and progression. Secondly, CNPY3 expression was validated in clinical samples and tumor cell lines. The results indicated that the findings of this study are reliable and worth further investigation. Thirdly, functional experiments indicated that cell proliferation, invasion, and migration were inhibited and cell apoptosis was promoted after CNPY3 knockdown. |
| Publish Date |
2024-07-12 15:55 |
| Citation |
<p>Gao XC, Zhou BH, Ji ZX, Li Q, Liu HN. CNPY3 is a prognostic factor in colon adenocarcinoma which is associated with immune infiltration and affects the PI3K/AKT pathway. <i>World J Gastrointest Oncol</i> 2024; 16(7): 3284-3298</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v16/i7/3284.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v16.i7.3284 |
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