Publication Name	World Journal of Virology
Manuscript ID	95709
Country	United States

Received	2024-04-16 17:16
Peer-Review Started	2024-04-16 17:16
To Make the First Decision
Return for Revision	2024-05-11 07:46
Revised	2024-05-27 09:47
Second Decision	2024-06-19 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-06-19 09:57
Articles in Press	2024-06-19 09:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-06-26 00:27
Publish the Manuscript Online	2024-08-29 07:51

ISSN	2220-3249 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Critical Care Medicine
Manuscript Type	Systematic Reviews
Article Title	Dosage and utilization of dexamethasone in the management of COVID-19: A critical review
Manuscript Source	Invited Manuscript
All Author List	Imran Sethi, Asim Shaikh, Musa Sethi, Hira Khalid Chohan, Sheraz Younus, Syed A Khan and Salim Surani
Funding Agency and Grant Number
Corresponding Author	Salim Surani, FACP, FCCP, MD, MHSc, Adjunct Professor, Department of Medicine and Pharmacology, Texas A and M University, 40 Bizzell Street, College Station, TX 77843, United States. srsurani@hotmail.com
Key Words	COVID-19; Steroids; Corticosteroids; Steroid dosage; Critical care; Corona virus
Core Tip	The role of steroid dosing in coronavirus disease 2019 (COVID-19) patients remains a critical area of focus especially concerning the reduction of COVID-19-associated mortality and improvement of overall serious outcomes. Numerous trials have recently been published evaluating outcomes with different steroid dosage regimens. Our meta-analysis shows that higher steroid dosing does not significantly improve serious outcomes and does not result in the reduction of serious adverse events. Therefore, barring additional studies evaluating the role of higher dosages according to stratification of various demographic factors, we do not recommend escalating doses of steroids to curb mortality or hospital stay duration in critical patients.
Publish Date	2024-08-29 07:51
Citation	<p>Sethi I, Shaikh A, Sethi M, Chohan HK, Younus S, Khan SA, Surani S. Dosage and utilization of dexamethasone in the management of COVID-19: A critical review. <i>World J Virol</i> 2024; 13(3): 95709</p>
URL	https://www.wjgnet.com/2220-3249/full/v13/i3/95709.htm
DOI	https://dx.doi.org/10.5501/wjv.v13.i3.95709

Full Article (PDF)	WJV-13-95709-with-cover.pdf
PRISMA 2009 Checklist	95709-PRISMA-2009-Checklist.pdf
Manuscript File	95709_Auto_Edited-JLW.docx
Answering Reviewers	95709-answering-reviewers.pdf
Audio Core Tip	95709-audio.m4a
Biostatistics Review Certificate	95709-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	95709-conflict-of-interest-statement.pdf
Copyright License Agreement	95709-copyright-assignment.pdf
Peer-review Report	95709-peer-reviews.pdf
Scientific Misconduct Check	95709-scientific-misconduct-check.png
Scientific Editor Work List	95709-scientific-editor-work-list.pdf
CrossCheck Report	95709-crosscheck-report.pdf