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7/24/2024 2:33:02 PM | Browse: 508 | Download: 815
Publication Name World Journal of Cardiology
Manuscript ID 95713
Country Sudan
Received
2024-04-16 18:12
Peer-Review Started
2024-04-16 18:12
First Decision by Editorial Office Director
2024-05-11 07:45
Return for Revision
2024-05-11 07:45
Revised
2024-05-20 18:19
Publication Fee Transferred
Second Decision by Editor
2024-06-05 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2024-06-05 08:04
Articles in Press
2024-06-05 08:04
Edit the Manuscript by Language Editor
2024-06-22 17:59
Typeset the Manuscript
2024-06-28 14:26
Publish the Manuscript Online
2024-07-24 13:09
ISSN 1949-8462 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Minireviews
Article Title Proprotein convertase subtilisin/kexin type 9 inhibitors in peripheral artery disease: Review of efficacy, safety, and outcomes
Manuscript Source Unsolicited Manuscript
All Author List Moiud Mohyeldin, Ahmed S Abuelgasim and Ahmed MG Mustafa
Funding Agency and Grant Number
Corresponding Author Moiud Mohyeldin, MD, Doctor, Doctor, Staff Physician, Department of Internal Medicine, University Of Medical Sciences and Technology, Ebed Khatim St, Khartoum 11111, Sudan. moiudahmed@gmail.com
Key Words Peripheral artery disease; Proprotein convertase subtilisin/kexin type 9 inhibitors; Cardiovascular risk reduction; Evolocumab; Alirocumab; Lipid-lowering therapy; Major adverse limb events; Clinical outcomes; Cost-effectiveness; Safety profile
Core Tip Evolocumab and alirocumab, which belong to the class of proprotein convertase subtilisin/kexin type 9 inhibitors, are effective in reducing cardiovascular events and major adverse limb events in peripheral artery disease patients. Despite their proven benefits, these inhibitors are underutilized in clinical practice, often due to providers’ lack of awareness and their concerns about cost. This highlights the need for further research to assess these inhibitors’ long-term effects and cost-effectiveness for specific patient groups.
Publish Date 2024-07-24 13:09
Citation

Mohyeldin M, Abuelgasim AS, Mustafa AM. Proprotein convertase subtilisin/kexin type 9 inhibitors in peripheral artery disease: Review of efficacy, safety, and outcomes. World J Cardiol 2024; 16(7): 397-401

URL https://www.wjgnet.com/1949-8462/full/v16/i7/397.htm
DOI https://dx.doi.org/10.4330/wjc.v16.i7.397
Full Article (PDF) WJC-16-397-with-cover.pdf