Publication Name	World Journal of Cardiology
Manuscript ID	95786
Country	Croatia

Received	2024-04-18 17:39
Peer-Review Started	2024-04-18 17:39
To Make the First Decision
Return for Revision	2024-07-12 08:17
Revised	2024-07-17 12:50
Second Decision	2024-07-22 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-07-23 10:14
Articles in Press	2024-07-23 10:14
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-07-27 22:44
Typeset the Manuscript	2024-07-31 03:01
Publish the Manuscript Online	2024-08-26 12:59

ISSN	1949-8462 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Endocrinology & Metabolism
Manuscript Type	Observational Study
Article Title	Sodium-dependent glucose transporter 2 inhibitors effects on myocardial function in patients with type 2 diabetes and asymptomatic heart failure
Manuscript Source	Invited Manuscript
All Author List	Petra Grubić Rotkvić, Luka Rotkvić, Ana Đuzel Čokljat and Maja Cigrovski Berković
Funding Agency and Grant Number
Corresponding Author	Petra Grubić Rotkvić, MD, PhD, Postdoctoral Fellow, Department of Cardiology, University Hospital Centre Zagreb, Kišpatićeva 12, Zagreb 10000, Croatia. petra.grubic84@gmail.com
Key Words	Sodium-dependent glucose transporters 2 inhibitors; Dipeptidyl peptidase-4 inhibitors; Type 2 diabetes mellitus; Heart failure; Diabetic cardiomyopathy; Cardiovascular disease
Core Tip	This study aimed to evaluate the outcomes regarding natriuretic peptide, oxidative stress, inflammation, blood pressure, heart rate, cardiac function, and body weight derived from our published prospective observational study, that assessed sodium-dependent glucose transporters inhibitors (SGLT2i) mechanisms of action in patients with type 2 diabetes and heart failure (HF) stages A and B on dual oral antidiabetic therapy. Mechanisms underlying favorable SGLT2i effects in HF are related to changes in body composition, reduced cardiac load, better cardiac function, and attenuation of sympathetic response, depending on the stage of HF and patients’ specific characteristics. Nevertheless, glycemic control itself could contribute to heart function improvement.
Publish Date	2024-08-26 12:59
Citation	<p>Grubić Rotkvić P, Rotkvić L, Đuzel Čokljat A, Cigrovski Berković M. Sodium-dependent glucose transporter 2 inhibitors effects on myocardial function in patients with type 2 diabetes and asymptomatic heart failure. <i>World J Cardiol</i> 2024; 16(8): 448-457</p>
URL	https://www.wjgnet.com/1949-8462/full/v16/i8/448.htm
DOI	https://dx.doi.org/10.4330/wjc.v16.i8.448

Full Article (PDF)	WJC-16-448-with-cover.pdf
STROBE Statement	95786-STROBE-statement.pdf
Manuscript File	95786_Auto_Edited_002707.docx
Answering Reviewers	95786-answering-reviewers.pdf
Audio Core Tip	95786-audio.mp3
Biostatistics Review Certificate	95786-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	95786-conflict-of-interest-statement.pdf
Copyright License Agreement	95786-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	95786-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	95786-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	95786-non-native-speakers.pdf
Peer-review Report	95786-peer-reviews.pdf
Scientific Misconduct Check	95786-scientific-misconduct-check.png
Scientific Editor Work List	95786-scientific-editor-work-list.pdf
CrossCheck Report	95786-crosscheck-report.png
CrossCheck Report	95786-crosscheck-report.pdf