Publication Name	World Journal of Clinical Oncology
Manuscript ID	95816
Country	China

Received	2024-04-19 08:17
Peer-Review Started	2024-04-19 08:17
To Make the First Decision
Return for Revision	2024-08-29 03:44
Revised	2024-09-11 04:13
Second Decision	2024-09-24 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-09-25 10:58
Articles in Press	2024-09-25 10:58
Publication Fee Transferred	2024-09-30 02:21
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-10-09 00:15
Publish the Manuscript Online	2024-10-14 07:12

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Genetics & Heredity
Manuscript Type	Case Report
Article Title	Whole exome sequencing identifies risk variants associated with intracranial epidermoid cyst deterioration: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Zhao-Na Song, Yan Cheng, Dan-Dan Wang, Ming-Jun Li, Xiang-Rong Zhao, Fa-Wang Li, Zhen Liu, Xiao-Ru Zhu, Xiao-Dong Jia, Yu-Fang Wang and Feng-Fan Liang
Funding Agency and Grant Number
Corresponding Author	Feng-Fan Liang, Doctor, Attending Doctor, Department of Radiotherapy, Liaocheng People's Hospital, Dongchang Road, Liaocheng 252000, Shandong Province, China. heroliang25@sina.com
Key Words	Intracranial epidermoid cyst; Squamous cell carcinoma; Whole exome sequencing; Variants; Case report
Core Tip	Intracranial epidermoid cyst (IEC) malignant transformation is an uncommon lesion, accompanied by the spread of tumor cells, resulting in a poor prognosis. In this report, we present the case of a 47-year-old woman who was diagnosed with a malignant transition from IEC to squamous cell carcinoma. After surgical resection and chemoradiotherapy, the patient's condition was effectively controlled. It's noteworthy that whole exome sequencing revealed the significant role of Gap junction protein beta 2 and Toll-like receptor 2 in IEC development.
Publish Date	2024-10-14 07:12
Citation	<p>Song ZN, Cheng Y, Wang DD, Li MJ, Zhao XR, Li FW, Liu Z, Zhu XR, Jia XD, Wang YF, Liang FF. Whole exome sequencing identifies risk variants associated with intracranial epidermoid cyst deterioration: A case report. <i>World J Clin Oncol</i> 2024; 15(11): 1428-1434</p>
URL	https://www.wjgnet.com/2218-4333/full/v15/i11/1428.htm
DOI	https://dx.doi.org/10.5306/wjco.v15.i11.1428

Full Article (PDF)	WJCO-15-1428-with-cover.pdf
CARE Checklist–2016	95816-CARE-Checklist-2016.pdf
Manuscript File	95816_Auto_Edited_033938.docx
Answering Reviewers	95816-answering-reviewers.pdf
Audio Core Tip	95816-audio.mp3
Conflict-of-Interest Disclosure Form	95816-conflict-of-interest-statement.pdf
Copyright License Agreement	95816-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s)	95816-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate	95816-non-native-speakers.pdf
Peer-review Report	95816-peer-reviews.pdf
Scientific Misconduct Check	95816-scientific-misconduct-check.png
Scientific Editor Work List	95816-scientific-editor-work-list.pdf
CrossCheck Report	95816-crosscheck-report.pdf