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7/26/2024 10:02:28 AM | Browse: 226 | Download: 365
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Received |
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2024-04-21 20:43 |
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Peer-Review Started |
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2024-04-21 20:43 |
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To Make the First Decision |
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Return for Revision |
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2024-05-30 19:05 |
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Revised |
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2024-06-20 01:09 |
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Second Decision |
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2024-07-03 02:41 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-07-03 09:46 |
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Articles in Press |
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2024-07-03 09:46 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-07-11 02:52 |
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Publish the Manuscript Online |
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2024-07-26 08:29 |
| ISSN |
2222-0682 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https: //creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Palliative care for end-stage liver disease and acute on chronic liver failure: A systematic review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Vakaola I Pulotu Mafi and Jonathan Soldera |
| Funding Agency and Grant Number |
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| Corresponding Author |
Jonathan Soldera, MD, MSc, PhD, Instructor, Post-Graduate Program, Acute Medicine, University of South Wales, Llantwit Road, Pontypridd, Cardiff CF37 1DL, United Kingdom. jonathansoldera@gmail.com |
| Key Words |
End stage liver disease; Acute on chronic liver failure; Palliative care; Liver transplantation; Quality of life |
| Core Tip |
This systematic review addresses the underexplored utilization of palliative care (PC) in patients with end stage liver disease (ESLD) and acute on chronic liver failure (ACLF), a demographic traditionally underserved. ESLD and ACLF are characterized by grim prognoses, substantial care costs, explicit patient suffering, and elevated mortality rates. Despite liver transplantation (LT) being a curative option, accessibility remains severely limited due to barriers such as donor scarcity, financial constraints, and inadequate social support. Even among those eligible for transplantation, a significant majority of ESLD patients are referred late for PC, typically within their final couple of weeks of life. PC offers notable benefits, including amelioration of symptom burden, reduced depressive symptoms, lower readmission rates, and shorter hospital stays. However, optimal utilization of PC faces barriers such as the allure of transplants and misconceptions about PC. A comprehensive understanding of the pivotal role of PC in ESLD and ACLF treatment is crucial for all stakeholders, including healthcare providers, patients, and caregivers, to overcome these barriers. Future prospective randomized studies, irrespective of LT eligibility, are needed to strengthen the evidence supporting early integration of PC in the management of ESLD/ACLF patients. |
| Publish Date |
2024-07-26 08:29 |
| Citation |
<p>Mafi VIP, Soldera J. Palliative care for end-stage liver disease and acute on chronic liver failure: A systematic review. <i>World J Methodol</i> 2024; 14(4): 95904</p> |
| URL |
https://www.wjgnet.com/2222-0682/full/v14/i4/95904.htm |
| DOI |
https://dx.doi.org/10.5662/wjm.v14.i4.95904 |
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