Publication Name	World Journal of Stem Cells
Manuscript ID	96221
Country	Brazil

Received	2024-04-30 18:22
Peer-Review Started	2024-04-30 18:22
To Make the First Decision
Return for Revision	2024-07-11 04:58
Revised	2024-07-22 23:26
Second Decision	2024-08-29 02:47
Accepted by Journal Editor-in-Chief	2024-08-29 21:12
Accepted by Executive Editor-in-Chief	2024-09-23 09:07
Articles in Press	2024-09-23 09:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-10-10 12:28
Publish the Manuscript Online	2024-10-25 02:40

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Cell & Tissue Engineering
Manuscript Type	Minireviews
Article Title	Bioengineering breakthroughs: The impact of stem cell models on advanced therapy medicinal product development
Manuscript Source	Invited Manuscript
All Author List	José Mauro Granjeiro, Priscila Grion de Miranda Borchio, Icaro Paschoal Brito Ribeiro and Katiucia Batista Silva Paiva
Funding Agency and Grant Number	Funding Agency Grant Number São Paulo Research Foundation/FAPESP 2020/11564-6, 2019/27001-3 National Council for Scientific and Technological Development/CNPq 400030/2018-7 Network NanoHealth/FAPERJ E-26/10.000981/2019, E-26/010.000210/2019/FAPERJ
Corresponding Author	José Mauro Granjeiro, PhD, Senior Researcher, Division of Biological Metrology, The National Institute of Metrology, Quality, and Technology, Avenida Nossa Sra. das Graças, 50 - Xerém, Duque de Caxias 25250020, Rio de Janeiro, Brazil. jmgranjeiro@inmetro.gov.br
Key Words	Stem cells; Advanced therapy medicinal products; Tissue-engineered products; Health; Three-dimensional cell culture
Core Tip	Stem cells play a crucial role in tissue engineering by offering the potential for regenerating of damaged tissues, which is critical for developing advanced therapy medicinal products. Stem cells can differentiate into specific cell types and promote tissue repair through various mechanisms. When combined with tissue engineering techniques, stem cell therapy enhances cell viability, differentiation, and therapeutic efficacy, overcoming disease treatment limitations. However, translating stem cell research into approved clinical therapies has been challenging. Regulatory bodies have provided guidelines to ensure the safety and efficacy of advanced therapeutic products utilizing stem cells before the approval for clinical use.
Publish Date	2024-10-25 02:40
Citation	<p>Granjeiro JM, Borchio PGM, Ribeiro IPB, Paiva KBS. Bioengineering breakthroughs: The impact of stem cell models on advanced therapy medicinal product development. <i>World J Stem Cells</i> 2024; 16(10): 860-872</p>
URL	https://www.wjgnet.com/1948-0210/full/v16/i10/860.htm
DOI	https://dx.doi.org/10.4252/wjsc.v16.i10.860

Full Article (PDF)	WJSC-16-860-with-cover.pdf
Manuscript File	96221_Auto_Edited_032331.docx
Answering Reviewers	96221-answering-reviewers.pdf
Audio Core Tip	96221-audio.mp3
Conflict-of-Interest Disclosure Form	96221-conflict-of-interest-statement.pdf
Copyright License Agreement	96221-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	96221-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	96221-non-native-speakers.pdf
Peer-review Report	96221-peer-reviews.pdf
Journal Editor-in-Chief Review Report	96221-journal-editor-in-chief.pdf
Scientific Misconduct Check	96221-scientific-misconduct-check.png
Scientific Editor Work List	96221-scientific-editor-work-list.pdf
CrossCheck Report	96221-crosscheck-report.pdf