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11/22/2024 11:08:18 AM | Browse: 155 | Download: 333
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Received |
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2024-05-25 15:25 |
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Peer-Review Started |
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2024-05-25 15:25 |
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To Make the First Decision |
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Return for Revision |
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2024-06-20 04:47 |
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Revised |
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2024-06-23 14:24 |
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Second Decision |
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2024-07-22 02:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-07-23 10:23 |
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Articles in Press |
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2024-07-23 10:23 |
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Publication Fee Transferred |
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2024-07-29 14:37 |
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Edit the Manuscript by Language Editor |
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2024-08-08 13:46 |
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Typeset the Manuscript |
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2024-08-12 00:15 |
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Publish the Manuscript Online |
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2024-11-06 09:50 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Observational Study |
| Article Title |
Overexpression of proteasome 26S subunit non-ATPase 6 protein and its clinical pathological significance in intrahepatic cholangiocarcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhong-Qing Tang, Yu-Lu Tang, Kai Qin, Qi Li, Gang Chen, Yu-Bin Huang and Jian-Jun Li |
| Funding Agency and Grant Number |
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| Corresponding Author |
Jian-Jun Li, PhD, Surgeon, Department of General Surgery, The Second Affiliated Hospital of Guangxi Medical University, No. 166 East University Road, Xixiangtang District, Nanning 530007, Guangxi Zhuang Autonomous Region, China. lijianjunmail@163.com |
| Key Words |
Intrahepatic cholangiocarcinoma; Proteasome 26S subunit non-ATPase 6; Immunohistochemistry; Clustered regularly interspaced short palindromic repeat knockout screen; Clinicopathological characteristics |
| Core Tip |
This study examined the effect and clinicopathological characteristics of proteasome 26S subunit non-ATPase 6 (PSMD6) in intrahepatic cholangiocarcinoma (ICC). We discovered that the PSMD6 gene is essential to the proliferation of ICC cell lines. Furthermore, PSMD6 protein expression was markedly elevated in ICC specimens (P < 0.001), although it was not significantly correlated with patient age, gender, pathological grade, or tumor, node, metastasis stage (P > 0.05). These results indicate that PSMD6 may enhance the proliferation of ICC cells, thereby contributing to its oncogenic potential. |
| Publish Date |
2024-11-06 09:50 |
| Citation |
<p>Tang ZQ, Tang YL, Qin K, Li Q, Chen G, Huang YB, Li JJ. Overexpression of proteasome 26S subunit non-ATPase 6 protein and its clinical pathological significance in intrahepatic cholangiocarcinoma. <i>World J Hepatol</i> 2024; 16(11): 1282-1289</p> |
| URL |
https://www.wjgnet.com/1948-5182/full/v16/i11/1282.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v16.i11.1282 |
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