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8/22/2024 11:58:20 AM | Browse: 271 | Download: 792
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Received |
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2024-06-02 02:58 |
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Peer-Review Started |
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2024-06-02 02:58 |
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First Decision by Editorial Office Director |
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2024-07-09 19:55 |
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Return for Revision |
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2024-07-10 04:52 |
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Revised |
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2024-07-24 04:20 |
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Publication Fee Transferred |
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2024-08-02 13:27 |
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Second Decision by Editor |
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2024-08-02 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-08-02 09:18 |
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Articles in Press |
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2024-08-02 09:18 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-08-13 00:22 |
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Publish the Manuscript Online |
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2024-08-21 23:22 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical and Translational Research |
| Article Title |
Causal association between 731 immunocyte phenotypes and liver cirrhosis: A bidirectional two-sample mendelian randomization analysis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ying Li, Xin Quan, Yang Tai, Yu-Tong Wu, Bo Wei and Hao Wu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
No. 82270649 |
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| Corresponding Author |
Hao Wu, PhD, Doctor, Doctor, Professor, Department of Gastroenterology, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu 610041, Sichuan Province, China. hxxhwh@163.com |
| Key Words |
Liver cirrhosis; Immune cell; Immunocyte phenotype; Mendelian analysis; Causal association |
| Core Tip |
The causal relationship between immunocyte phenotypes and liver cirrhosis has not been fully elucidated. This bidirectional two-sample mendelian randomization study identified a significant causal association between 731 immunocyte phenotypes and liver cirrhosis. We found that 20 immunocyte phenotypes were associated with liver cirrhosis (P < 0.05), whereas liver cirrhosis was associated with 19 immunocyte phenotypes (P < 0.05). None of these associations showed heterogeneity or horizontal pleiotropy (P > 0.05). These findings provide novel directions for the treatment of liver cirrhosis. |
| Publish Date |
2024-08-21 23:22 |
| Citation |
Li Y, Quan X, Tai Y, Wu YT, Wei B, Wu H. Causal association between 731 immunocyte phenotypes and liver cirrhosis: A bidirectional two-sample mendelian randomization analysis. World J Hepatol 2024; 16(8): 1156-1166 |
| URL |
https://www.wjgnet.com/1948-5182/full/v16/i8/1156.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v16.i8.1156 |
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