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10/31/2024 10:55:01 AM | Browse: 107 | Download: 295
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Received |
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2024-08-16 07:58 |
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Peer-Review Started |
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2024-06-29 00:02 |
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To Make the First Decision |
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Return for Revision |
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2024-09-19 04:45 |
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Revised |
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2024-10-02 04:07 |
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Second Decision |
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2024-10-24 02:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-10-24 10:57 |
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Articles in Press |
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2024-10-24 10:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-10-26 00:34 |
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Publish the Manuscript Online |
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2024-10-31 07:40 |
| ISSN |
2220-315x (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Statins decrease the risk of hepatocellular carcinoma in metabolic dysfunction-associated steatotic liver disease: A systematic review and meta-analysis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Zahid Ijaz Tarar, Umer Farooq, Faisal Inayat, Sanket D Basida, Faisal Ibrahim, Mustafa Gandhi, Gul Nawaz, Arslan Afzal, Ammad J Chaudhary, Faisal Kamal, Ahmad H Ali and Yezaz A Ghouri |
| Funding Agency and Grant Number |
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| Corresponding Author |
Faisal Inayat, Department of Internal Medicine, Allama Iqbal Medical College, Allama Shabbir Ahmad Usmani Road, Faisal Town, Punjab 54550, Pakistan. faisalinayat@hotmail.com |
| Key Words |
Metabolic dysfunction-associated steatotic liver disease; Hepatocellular carcinoma; Statins; Lipophilic statin; Hydrophilic statin; Meta-analysis |
| Core Tip |
Current clinical evidence regarding the effect of statins on lowering the risk of hepatocellular carcinoma (HCC) among patients with metabolic dysfunction-associated steatotic liver disease (MASLD) is inconclusive. We performed a systematic review and meta-analysis of all the studies that evaluated the impact of statins on HCC occurrence in MASLD patients. The pooled data from four studies involving 291684 patients was included in the final analysis. Our findings show that statin use reduces the risk of HCC among patients with MASLD. The use of higher cumulative defined daily doses and lipophilic statins results in a significant reduction in HCC risk. |
| Publish Date |
2024-10-31 07:40 |
| Citation |
<p>Tarar ZI, Farooq U, Inayat F, Basida SD, Ibrahim F, Gandhi M, Nawaz G, Afzal A, Chaudhary AJ, Kamal F, Ali AH, Ghouri YA. Statins decrease the risk of hepatocellular carcinoma in metabolic dysfunction-associated steatotic liver disease: A systematic review and meta-analysis. <i>World J Exp Med</i> 2024; 14(4): 98543</p> |
| URL |
https://www.wjgnet.com/2220-315x/full/v14/i4/98543.htm |
| DOI |
https://dx.doi.org/10.5493/wjem.v14.i4.98543 |
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