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1/21/2025 9:40:07 AM | Browse: 66 | Download: 105
Publication Name World Journal of Clinical Oncology
Manuscript ID 99527
Country China
Received
2024-07-24 12:20
Peer-Review Started
2024-07-24 12:20
To Make the First Decision
Return for Revision
2024-09-15 01:34
Revised
2024-11-10 15:23
Second Decision
2024-12-30 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-12-30 08:38
Articles in Press
2024-12-30 08:38
Publication Fee Transferred
2024-11-18 05:14
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-01-13 03:28
Publish the Manuscript Online
2025-01-21 09:22
ISSN 2218-4333 (online)
Open Access Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Case Report
Article Title Efficacy of disitamab vedotin-containing therapy in metastatic colorectal cancer: A case report
Manuscript Source Unsolicited Manuscript
All Author List Hu-Cheng Yan, Yan Liu, You Feng, Jun-Ming Li, Lei-Ming Sheng, Xin Chen, Yu-Ping Xie and Na Li
Funding Agency and Grant Number
Corresponding Author Na Li, PhD, Department of Oncology, West China School of Public Health and West China Fourth Hospital, Sichuan University, No. 18 Section 3, Renmin South Road, Chengdu 610041, Sichuan Province, China. 281422934@qq.com
Key Words Disitamab vedotin; Human epidermal growth factor receptor 2; Overexpression; Metastatic colorectal cancer; Efficacy; Case report
Core Tip Colorectal cancer (CRC) is a leading cause of cancer-related mortality. In cases of metastatic CRC (mCRC) that is resistant to conventional chemotherapy, human epidermal growth factor receptor 2 (HER2)-targeted therapies have shown promise. We describe a 69-year-old woman with HER2-overexpressing mCRC, featuring an NRAS p.G12V mutation and microsatellite stability, who achieved an excellent response to disitamab vedotin treatment. This case is notable as it is the first recorded observation of a notable clinical response to anti-HER2 therapy in an mCRC patient with HER2 overexpression and an NRAS p.G12V mutation.
Publish Date 2025-01-21 09:22
Citation <p>Yan HC, Liu Y, Feng Y, Li JM, Sheng LM, Chen X, Xie YP, Li N. Efficacy of disitamab vedotin-containing therapy in metastatic colorectal cancer: A case report. <i>World J Clin Oncol</i> 2025; 16(3): 99527</p>
URL https://www.wjgnet.com/2218-4333/full/v16/i3/99527.htm
DOI https://dx.doi.org/10.5306/wjco.v16.i3.99527
Full Article (PDF) WJCO-16-99527-with-cover.pdf
CARE Checklist–2016 99527-CARE-Checklist-2016.pdf
Manuscript File 99527_Auto_Edited_122135.docx
Answering Reviewers 99527-answering-reviewers.pdf
Audio Core Tip 99527-audio.mp3
Conflict-of-Interest Disclosure Form 99527-conflict-of-interest-statement.pdf
Copyright License Agreement 99527-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 99527-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 99527-non-native-speakers.pdf
Peer-review Report 99527-peer-reviews.pdf
Scientific Misconduct Check 99527-scientific-misconduct-check.png
Scientific Editor Work List 99527-scientific-editor-work-list.pdf
CrossCheck Report 99527-crosscheck-report.pdf