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9/20/2024 1:04:30 PM | Browse: 121 | Download: 244
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Received |
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2024-07-24 13:15 |
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Peer-Review Started |
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2024-07-24 13:15 |
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To Make the First Decision |
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Return for Revision |
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2024-08-17 23:49 |
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Revised |
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2024-08-28 14:58 |
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Second Decision |
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2024-09-09 02:45 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-09-09 04:43 |
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Articles in Press |
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2024-09-09 04:43 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-09-12 17:00 |
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Publish the Manuscript Online |
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2024-09-20 08:50 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Editorial |
| Article Title |
Reconceptualization of immune checkpoint inhibitor-associated gastritis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ying-Fang Deng, Xian-Shu Cui and Liang Wang |
| Funding Agency and Grant Number |
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| Corresponding Author |
Liang Wang, MD, Attending Doctor, Department of Gastrointestinal Oncology Surgery, Affiliated Hospital of Qinghai University, No. 29 Tongren Road, Xining 810000, Qinghai Province, China. wangliang19911128@163.com |
| Key Words |
Programmed cell death receptor-1; Programmed cell death-ligand 1; Cytotoxic T lymphocyte-associated antigen 4; Immune-related adverse events; Immune-related gastritis |
| Core Tip |
With the widespread application of immunotherapy, the incidence of immune-related gastritis has increased than before. However, the diagnosis of immune-related gastritis is somewhat challenging due to its atypical clinical symptoms and lack of specific findings in serological tests. Although endoscopy and histopathological examination are valuable for immune-related gastritis diagnosis, differential diagnosis for different diseases (such as autoimmune gastritis) is still necessary. The treatment of immune-related gastritis should be individualized based on the patient's specific situation. The occurrence and management of immune-related adverse events (irAEs), as well as whether to continue treatment with immune checkpoint inhibitors (ICIs) after resolution, are major challenges in clinical practice. Studies have shown that for patients with grade 2-3 irAEs, ICI treatment can be considered for reinitiation when symptoms regress to grade 0-1, preferably using a different class of ICIs. For grade 4 irAEs, ICIs should be permanently discontinued. |
| Publish Date |
2024-09-20 08:50 |
| Citation |
<p>Deng YF, Cui XS, Wang L. Reconceptualization of immune checkpoint inhibitor-associated gastritis. <i>World J Gastroenterol</i> 2024; 30(36): 4031-4035</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v30/i36/4031.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v30.i36.4031 |
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