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11/29/2024 9:03:30 AM | Browse: 28 | Download: 43
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Received |
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2024-07-27 02:37 |
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Peer-Review Started |
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2024-07-27 02:37 |
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To Make the First Decision |
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Return for Revision |
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2024-09-04 02:16 |
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Revised |
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2024-09-17 16:58 |
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Second Decision |
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2024-10-22 03:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-10-22 05:38 |
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Articles in Press |
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2024-10-22 05:38 |
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Publication Fee Transferred |
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2024-10-24 03:20 |
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Edit the Manuscript by Language Editor |
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2024-11-13 03:29 |
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Typeset the Manuscript |
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2024-11-19 07:44 |
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Publish the Manuscript Online |
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2024-11-29 08:40 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Observational Study |
Article Title |
Link between pharyngeal acid reflux episodes and the effectiveness of proton pump inhibitor therapy
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Yen-Yang Chen, Chen-Chi Wang, Chun-Yi Chuang, Yung-An Tsou, Yen-Chun Peng, Chi-Sen Chang and Han-Chung Lien |
Funding Agency and Grant Number |
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Corresponding Author |
Han-Chung Lien, MD, PhD, Associate Professor, Division of Gastroenterology, Center for Functional Esophageal Disorders, Taichung Veterans General Hospital, No. 1650 Taiwan Boulevard, Section 4, Taichung 435, Taiwan. lhc@vghtc.gov.tw |
Key Words |
Pharyngeal acid reflux episodes; Laryngopharyngeal reflux; Hypopharyngeal multichannel intraluminal impedance-potential of hydrogen; 3- potential of hydrogen-sensor; Proton pump inhibitors |
Core Tip |
This study examines the link between pharyngeal acid reflux (PAR) episodes and the effectiveness of proton pump inhibitor (PPI) therapy in laryngopharyngeal reflux (LPR) patients. Using specific potential of hydrogen criteria for PAR episodes detected by hypopharyngeal multichannel intraluminal impedance-potential of hydrogen, researchers found that patients with ≥ 2 baseline PAR episodes had a significantly higher response rate (73%) to PPI therapy compared to those without acidic reflux (33%). These findings underscore the importance of hypopharyngeal reflux monitoring, as PAR episodes appear to be crucial in predicting PPI efficacy. Hence, the authors recommend a personalized approach to LPR diagnosis and treatment in order to enhance patient outcomes. |
Publish Date |
2024-11-29 08:40 |
Citation |
<p>Chen YY, Wang CC, Chuang CY, Tsou YA, Peng YC, Chang CS, Lien HC. Link between pharyngeal acid reflux episodes and the effectiveness of proton pump inhibitor therapy. <i>World J Gastroenterol</i> 2024; 30(48): 5162-5173</p> |
URL |
https://www.wjgnet.com/1007-9327/full/v30/i48/5162.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v30.i48.5162 |
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