Publication Name	World Journal of Gastroenterology
Manuscript ID	99684
Country	China

Received	2024-07-27 19:52
Peer-Review Started	2024-07-27 19:52
To Make the First Decision
Return for Revision	2024-08-05 20:21
Revised	2024-08-08 04:57
Second Decision	2024-09-05 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-09-05 06:20
Articles in Press	2024-09-05 06:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-09-09 00:32
Publish the Manuscript Online	2024-09-20 08:50

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Endocrinology & Metabolism
Manuscript Type	Editorial
Article Title	Glucagon-like peptide-1 receptor agonists: Exploring the mechanisms from glycemic control to treatment of multisystemic diseases
Manuscript Source	Invited Manuscript
All Author List	Mo-Wei Kong, Yang Yu, Ying Wan, Yu Gao and Chun-Xiang Zhang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China U23A20398 National Natural Science Foundation of China 82030007 Sichuan Science and Technology Program 2022YFS0578
Corresponding Author	Chun-Xiang Zhang, MD, Dean, Professor, Department of Cardiology, The Affiliated Hospital of Southwest Medical University, No. 1735 West Harrison Street, Luzhou 646000, Sichuan Province, China. zhangchx999@163.com
Key Words	Glucagon-like peptide-1 receptor agonists; Glycemic control; Multisystem diseases; Mechanism of action; Cardiovascular protection; Renal disease; Bone metabolism; Non-alcoholic fatty liver disease; Neuroprotection; Polycystic ovary syndrome
Core Tip	This editorial serves as an extension to the insightful research by Soresi and Giannitrapani, initially presented in the World Journal of Gastroenterology. We revisit their focus on the role of glucagon-like peptide-1 receptor agonists (GLP-1RAs) in treating metabolic dysfunction-associated fatty liver disease, and supplement their work by exploring the broader systemic applications of GLP-1RAs. Our aim is to provide a comprehensive overview of the mechanisms of action of GLP-1RAs and to highlight the latest research developments, emphasizing their potential in managing a variety of diseases. We emphasize the multifaceted therapeutic value of GLP-1RAs and encourage further investigation into their clinical utility across different medical specialties.
Publish Date	2024-09-20 08:50
Citation	<p>Kong MW, Yu Y, Wan Y, Gao Y, Zhang CX. Glucagon-like peptide-1 receptor agonists: Exploring the mechanisms from glycemic control to treatment of multisystemic diseases. <i>World J Gastroenterol</i> 2024; 30(36): 4036-4043</p>
URL	https://www.wjgnet.com/1007-9327/full/v30/i36/4036.htm
DOI	https://dx.doi.org/10.3748/wjg.v30.i36.4036

Full Article (PDF)	WJG-30-4036-with-cover.pdf
Manuscript File	99684_Auto_Edited_033539.docx
Answering Reviewers	99684-answering-reviewers.pdf
Audio Core Tip	99684-audio.wav
Conflict-of-Interest Disclosure Form	99684-conflict-of-interest-statement.pdf
Copyright License Agreement	99684-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	99684-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	99684-non-native-speakers.pdf
Peer-review Report	99684-peer-reviews.pdf
Scientific Misconduct Check	99684-scientific-misconduct-check.png
Scientific Editor Work List	99684-scientific-editor-work-list.pdf
CrossCheck Report	99684-crosscheck-report.png
CrossCheck Report	99684-crosscheck-report.pdf