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10/16/2024 7:18:23 AM | Browse: 233 | Download: 487
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Received |
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2024-07-27 20:17 |
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Peer-Review Started |
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2024-07-27 20:17 |
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First Decision by Editorial Office Director |
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2024-08-17 04:21 |
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2024-08-17 04:21 |
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Revised |
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2024-09-05 18:03 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2024-09-24 02:41 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-09-24 06:31 |
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Articles in Press |
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2024-09-24 06:31 |
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Edit the Manuscript by Language Editor |
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2024-10-01 01:27 |
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Typeset the Manuscript |
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2024-10-13 16:06 |
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Publish the Manuscript Online |
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2024-10-16 06:29 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Review |
| Article Title |
Advancing diabetes management: Exploring pancreatic beta-cell restoration’s potential and challenges
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Mona Mohamed Ibrahim Abdalla |
| Funding Agency and Grant Number |
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| Corresponding Author |
Mona Mohamed Ibrahim Abdalla, MSc, PhD, Senior Lecturer, Department of Human Biology, School of Medicine, International Medical University, No. 126, Jln Jalil Perkasa 19, Bukit Jalil 57000, Kuala Lumpur, Malaysia. monamohamed@imu.edu.my |
| Key Words |
Molecular therapeutics; Gene editing; Stem cell therapy; Regenerative medicine; Beta cell regeneration; Diabetes therapies |
| Core Tip |
Diabetes, a disease of uncontrolled blood sugar, arises from the loss or dysfunction of insulin-producing beta cells within the pancreas. While traditional management focuses on external insulin, cutting-edge research explores restoring these beta cells. Strategies include stem cell therapy, gene editing, and discovering molecules that promote beta cell growth. However, ensuring safety, overcoming biological complexities, and navigating the ethics of stem cell use present challenges. Through continued research, funding, and a patient-centered approach, beta-cell restoration offers the potential to move diabetes care from management to a possible cure. |
| Publish Date |
2024-10-16 06:29 |
| Citation |
Abdalla MMI. Advancing diabetes management: Exploring pancreatic beta-cell restoration’s potential and challenges. World J Gastroenterol 2024; 39(40): 4339-4353 |
| URL |
https://www.wjgnet.com/1007-9327/full/v30/i40/4339.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v30.i40.4339 |
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