Publication Name	World Journal of Gastroenterology
Manuscript ID	99685
Country	Malaysia

Received	2024-07-27 20:17
Peer-Review Started	2024-07-27 20:17
To Make the First Decision
Return for Revision	2024-08-17 04:21
Revised	2024-09-05 18:03
Second Decision	2024-09-24 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-09-24 06:31
Articles in Press	2024-09-24 06:31
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-10-01 01:27
Typeset the Manuscript	2024-10-13 16:06
Publish the Manuscript Online	2024-10-16 06:29

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Endocrinology & Metabolism
Manuscript Type	Review
Article Title	Advancing diabetes management: Exploring pancreatic beta-cell restoration’s potential and challenges
Manuscript Source	Invited Manuscript
All Author List	Mona Mohamed Ibrahim Abdalla
Funding Agency and Grant Number
Corresponding Author	Mona Mohamed Ibrahim Abdalla, MSc, PhD, Senior Lecturer, Department of Human Biology, School of Medicine, International Medical University, No. 126, Jln Jalil Perkasa 19, Bukit Jalil 57000, Kuala Lumpur, Malaysia. monamohamed@imu.edu.my
Key Words	Diabetes therapies; Beta cell regeneration; Regenerative medicine; Stem cell therapy; Gene editing; Molecular therapeutics
Core Tip	Diabetes, a disease of uncontrolled blood sugar, arises from the loss or dysfunction of insulin-producing beta cells within the pancreas. While traditional management focuses on external insulin, cutting-edge research explores restoring these beta cells. Strategies include stem cell therapy, gene editing, and discovering molecules that promote beta cell growth. However, ensuring safety, overcoming biological complexities, and navigating the ethics of stem cell use present challenges. Through continued research, funding, and a patient-centered approach, beta-cell restoration offers the potential to move diabetes care from management to a possible cure.
Publish Date	2024-10-16 06:29
Citation	<p>Abdalla MMI. Advancing diabetes management: Exploring pancreatic beta-cell restoration’s potential and challenges. <i>World J Gastroenterol</i> 2024; 39(40): 4339-4353</p>
URL	https://www.wjgnet.com/1007-9327/full/v30/i40/4339.htm
DOI	https://dx.doi.org/10.3748/wjg.v30.i40.4339

Full Article (PDF)	WJG-30-4339-with-cover.pdf
Manuscript File	99685_Auto_Edited_030239.docx
Answering Reviewers	99685-answering-reviewers.pdf
Audio Core Tip	99685-audio.mp3
Conflict-of-Interest Disclosure Form	99685-conflict-of-interest-statement.pdf
Copyright License Agreement	99685-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	99685-non-native-speakers.pdf
Peer-review Report	99685-peer-reviews.pdf
Scientific Misconduct Check	99685-scientific-misconduct-check.png
Scientific Editor Work List	99685-scientific-editor-work-list.pdf
CrossCheck Report	99685-crosscheck-report.pdf