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11/12/2024 2:45:35 PM | Browse: 56 | Download: 81
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Received |
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2024-07-31 00:33 |
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Peer-Review Started |
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2024-07-31 00:33 |
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To Make the First Decision |
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Return for Revision |
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2024-09-24 12:21 |
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Revised |
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2024-10-05 18:28 |
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Second Decision |
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2024-10-22 02:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-10-22 08:00 |
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Articles in Press |
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2024-10-22 08:00 |
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Publication Fee Transferred |
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2024-10-24 20:04 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-11-01 06:42 |
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Publish the Manuscript Online |
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2024-11-12 12:23 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pathology |
| Manuscript Type |
Case Report |
| Article Title |
Mixed pancreatic ductal adenocarcinoma and well-differentiated neuroendocrine tumor: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiaofeng Zhao, Tina Bocker Edmonston, Ronald Miick and Upasana Joneja |
| Funding Agency and Grant Number |
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| Corresponding Author |
Xiaofeng Zhao, MD, PhD, Assistant Professor, Department of Pathology, Cooper University Hospital, 1 Cooper Plz, Camden, NJ 08103, United States. zhao-xiaofeng@cooperhealth.edu |
| Key Words |
Pancreatic mixed neuroendocrine-non-neuroendocrine neoplasms; Pancreatic adenocarcinoma; Grade 1 well-differentiated neuroendocrine tumor; Molecular profile; Collision tumor; Case report |
| Core Tip |
Pancreatic mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) are rare malignancies affecting the pancreas, recognized by the World Health Organization as neoplasms composed of morphologically recognizable neuroendocrine and non-neuroendocrine components, each constituting ≥ 30% of the tumor volume. However, whether the tumor should be classified as MiNENs or collision tumor when there is clear divergence in histology and molecular profiles for each component is still debatable. This paper reports a rare case with high grade adenocarcinoma admixed with low grade neuroendocrine tumor in pancreas, which are demonstrated to have distinct molecular profiles. We discuss the potential impacts of tumor classification on staging and clinical management, hoping to encourage more discussions and studies on this rare entity. |
| Publish Date |
2024-11-12 12:23 |
| Citation |
<p>Zhao X, Bocker Edmonston T, Miick R, Joneja U. Mixed pancreatic ductal adenocarcinoma and well-differentiated neuroendocrine tumor: A case report. <i>World J Gastrointest Oncol</i> 2024; 16(12): 4738-4745</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v16/i12/4738.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v16.i12.4738 |
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