Publication Name	World Journal of Gastroenterology
Manuscript ID	99954
Country	China

Received	2024-08-21 06:21
Peer-Review Started	2024-08-03 18:01
To Make the First Decision
Return for Revision	2024-10-11 03:51
Revised	2024-10-24 02:34
Second Decision	2024-11-19 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-19 06:28
Articles in Press	2024-11-19 06:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-11-27 08:30
Publish the Manuscript Online	2024-12-09 10:40

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Letter to the Editor
Article Title	Transfer RNA-derived small RNA serves as potential non-invasive diagnostic marker and a novel therapeutic target for acute pancreatitis
Manuscript Source	Invited Manuscript
All Author List	Jing Zhang and Chun-Lin Ou
Funding Agency and Grant Number	Funding Agency Grant Number the Central South University Innovation-Driven Research Programme 2023CXQD075
Corresponding Author	Chun-Lin Ou, Associate Professor, PhD, Department of Pathology, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Changsha 410008, Hunan Province, China. ouchunlin@csu.edu.cn
Key Words	Transfer RNA derived small RNAs; Acute pancreatitis; Liquid biopsy; biomarker; Cell pyroptosis; Ferroptosis
Core Tip	The dysregulated expression of tRNA-derived small RNAs (tsRNAs) in acute pancreatitis (AP) reveals the molecular mechanism by which tsRNAs affect the occurrence and development of AP, and can be used as diagnostic markers and potential therapeutic targets. In cell and animal models, the inhibition or overexpression of tsRNA has been shown to influence AP development. The results showed that tsRNAs accelerated AP progression by inducing an increase in inflammatory factors and promoting cell death (including pyroptosis and ferroptosis).
Publish Date	2024-12-09 10:40
Citation	<p>Zhang J, Ou CL. Transfer RNA-derived small RNA serves as potential non-invasive diagnostic marker and a novel therapeutic target for acute pancreatitis. <i>World J Gastroenterol</i> 2025; 31(1): 99954</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i1/99954.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i1.99954

Full Article (PDF)	WJG-31-99954-with-cover.pdf
Manuscript File	99954_Auto_Edited_035243.docx
Answering Reviewers	99954-answering-reviewers.pdf
Audio Core Tip	99954-audio.mp3
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Scientific Editor Work List	99954-scientific-editor-work-list.pdf
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CrossCheck Report	99954-crosscheck-report.pdf