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Articles Published Processes
12/18/2024 7:36:02 AM | Browse: 30 | Download: 127
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Received |
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2024-08-20 01:08 |
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Peer-Review Started |
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2024-08-05 14:05 |
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To Make the First Decision |
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Return for Revision |
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2024-11-16 05:34 |
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Revised |
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2024-11-17 14:27 |
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Second Decision |
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2024-11-22 03:33 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-11-22 13:00 |
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Articles in Press |
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2024-11-22 13:00 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-12-05 01:09 |
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Publish the Manuscript Online |
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2024-12-18 07:36 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Microbiology |
Manuscript Type |
Letter to the Editor |
Article Title |
Interplay between creeping fat and gut microbiota: A brand-new perspective on fecal microbiota transplantation in Crohn's disease
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Manuscript Source |
Invited Manuscript |
All Author List |
Ying Wang and Jie Liu |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Jie Liu, MD, Department of Gastroenterology, The First Affiliated Hospital of University of Science and Technology of China, No. 17 Lujiang Road, Hefei 230001, Anhui Province, China. feixilj@163.com |
Key Words |
Crohn's disease; Mesenteric adipose tissue; Creeping fat; Fecal microbiota transplantation; Gut microbiota |
Core Tip |
Some studies have indicated that dysbiosis of the gut microbiota is a significant characteristic in the development of Crohn's disease (CD). However, the functional role of translocated microbiota in the mesenteric adipose tissue (MAT) of CD patients remains ambiguous. Evidence has shown that the translocation of viable microbiota into human MAT can polarize macrophages, leading to adipogenesis within the MAT and contributing to the formation of creeping fat (CrF) in individuals with CD. Nonetheless, it remains an important inquiry to elucidate the role of MAT-associated microbiota in the pathogenesis of CD. This manuscript aims to discuss the article by Wu et al, which explores the potential therapeutic value of fecal microbiota transplantation in the management of CD. Study by Wu et al suggested that the interactions among gut microbiota, MAT hypertrophy, and intestinal fibrosis may mutually reinforce one another in the pathogenesis of CD. Consequently, targeting MAT and CrF may hold promise as a therapeutic strategy for patients suffering from CD. |
Publish Date |
2024-12-18 07:36 |
Citation |
<p>Wang Y, Liu J. Interplay between creeping fat and gut microbiota: A brand-new perspective on fecal microbiota transplantation in Crohn's disease. <i>World J Gastroenterol</i> 2025; 31(2): 100024</p> |
URL |
https://www.wjgnet.com/1007-9327/full/v31/i2/100024.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v31.i2.100024 |
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