BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
12/18/2024 7:36:02 AM | Browse: 30 | Download: 127
Publication Name World Journal of Gastroenterology
Manuscript ID 100024
Country China
Received
2024-08-20 01:08
Peer-Review Started
2024-08-05 14:05
To Make the First Decision
Return for Revision
2024-11-16 05:34
Revised
2024-11-17 14:27
Second Decision
2024-11-22 03:33
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-11-22 13:00
Articles in Press
2024-11-22 13:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-12-05 01:09
Publish the Manuscript Online
2024-12-18 07:36
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Microbiology
Manuscript Type Letter to the Editor
Article Title Interplay between creeping fat and gut microbiota: A brand-new perspective on fecal microbiota transplantation in Crohn's disease
Manuscript Source Invited Manuscript
All Author List Ying Wang and Jie Liu
ORCID
Author(s) ORCID Number
Ying Wang http://orcid.org/0000-0002-8983-1307
Jie Liu http://orcid.org/0000-0001-6079-7566
Funding Agency and Grant Number
Corresponding Author Jie Liu, MD, Department of Gastroenterology, The First Affiliated Hospital of University of Science and Technology of China, No. 17 Lujiang Road, Hefei 230001, Anhui Province, China. feixilj@163.com
Key Words Crohn's disease; Mesenteric adipose tissue; Creeping fat; Fecal microbiota transplantation; Gut microbiota
Core Tip Some studies have indicated that dysbiosis of the gut microbiota is a significant characteristic in the development of Crohn's disease (CD). However, the functional role of translocated microbiota in the mesenteric adipose tissue (MAT) of CD patients remains ambiguous. Evidence has shown that the translocation of viable microbiota into human MAT can polarize macrophages, leading to adipogenesis within the MAT and contributing to the formation of creeping fat (CrF) in individuals with CD. Nonetheless, it remains an important inquiry to elucidate the role of MAT-associated microbiota in the pathogenesis of CD. This manuscript aims to discuss the article by Wu et al, which explores the potential therapeutic value of fecal microbiota transplantation in the management of CD. Study by Wu et al suggested that the interactions among gut microbiota, MAT hypertrophy, and intestinal fibrosis may mutually reinforce one another in the pathogenesis of CD. Consequently, targeting MAT and CrF may hold promise as a therapeutic strategy for patients suffering from CD.
Publish Date 2024-12-18 07:36
Citation <p>Wang Y, Liu J. Interplay between creeping fat and gut microbiota: A brand-new perspective on fecal microbiota transplantation in Crohn's disease. <i>World J Gastroenterol</i> 2025; 31(2): 100024</p>
URL https://www.wjgnet.com/1007-9327/full/v31/i2/100024.htm
DOI https://dx.doi.org/10.3748/wjg.v31.i2.100024
Full Article (PDF) WJG-31-100024-with-cover.pdf
Manuscript File 100024_Auto_Edited_100008.docx
Answering Reviewers 100024-answering-reviewers.pdf
Audio Core Tip 100024-audio.m4a
Conflict-of-Interest Disclosure Form 100024-conflict-of-interest-statement.pdf
Copyright License Agreement 100024-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 100024-non-native-speakers.pdf
Peer-review Report 100024-peer-reviews.pdf
Scientific Misconduct Check 100024-scientific-misconduct-check.png
Scientific Editor Work List 100024-scientific-editor-work-list.pdf
CrossCheck Report 100024-crosscheck-report.pdf