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Articles Published Processes
1/22/2025 9:25:50 AM | Browse: 87 | Download: 377
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Received |
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2024-08-20 01:16 |
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Peer-Review Started |
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2024-08-05 16:28 |
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To Make the First Decision |
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Return for Revision |
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2024-11-24 06:13 |
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Revised |
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2024-11-26 06:28 |
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Second Decision |
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2024-12-06 02:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-12-06 08:00 |
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Articles in Press |
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2024-12-06 08:00 |
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Publication Fee Transferred |
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2024-11-29 02:21 |
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Edit the Manuscript by Language Editor |
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2024-12-09 01:57 |
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Typeset the Manuscript |
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2024-12-19 09:32 |
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Publish the Manuscript Online |
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2025-01-22 09:25 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Emergency Medicine |
| Manuscript Type |
Minireviews |
| Article Title |
Extracellular matrix gene set and microRNA network in intestinal ischemia-reperfusion injury: RNA sequencing insights for diagnosis and therapy
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Dao-Jian Xu, Guo-Tao Wang and Qiang Zhong |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Health Science and Technology Programme of Zhejiang Province |
2022KY1391 |
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| Corresponding Author |
Dao-Jian Xu, Assistant Professor, MD, Department of Emergency, Taizhou Municipal Hospital, No. 381 Zhongshan East Road, Jiaojiang District, Taizhou 318000, Zhejiang Province, China. jjxudaojian@163.com |
| Key Words |
Diagnostic biomarkers; Extracellular matrix; Gene expression; Intestinal ischemia-reperfusion injury; Matrix metalloproteinases; MicroRNA; Treatment strategies |
| Core Tip |
This review systematically summarizes the diagnostic and therapeutic potential of extracellular matrix (ECM) gene sets and microRNA (miRNA) regulatory networks in intestinal ischemia-reperfusion injury (IRII). We review the critical roles of ECM in the pathological processes of IRII and discuss the mechanisms by which specific miRNAs regulate inflammation, apoptosis, and ECM remodeling. Based on these molecular insights, potential diagnostic biomarkers and treatment strategies, including miRNA-targeted therapy and ECM component modulation, demonstrate significant clinical translational prospects. In summary, the roles of ECM and miRNAs in IRII provide new research directions aimed at improving patient diagnosis and treatment outcomes. |
| Publish Date |
2025-01-22 09:25 |
| Citation |
<p>Xu DJ, Wang GT, Zhong Q. Extracellular matrix gene set and microRNA network in intestinal ischemia-reperfusion injury: RNA sequencing insights for diagnosis and therapy. <i>World J Gastrointest Surg</i> 2025; 17(2): 100034</p> |
| URL |
https://www.wjgnet.com/1948-9366/full/v17/i2/100034.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v17.i2.100034 |
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