ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Case Control Study |
Article Title |
Differences in diversity and composition of mucosa-associated colonic microbiota in colorectal cancer and non-colorectal cancer in Indonesia
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Nikko Darnindro, Murdani Abdullah, Ninik Sukartini, Cleopas M Rumende, Amanda Pitarini, Saskia Aziza Nursyirwan, Achmad Fauzi, Dadang Makmun, Erni J Nelwan, Hamzah Shatri, Ikhwan Rinaldi and Caroline Tanadi |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Nikko Darnindro, MD, Division of Gastroenterology, Pancreatobiliary and Digestive Endoscopy, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo National General Hospital, Jl. Pangeran Diponegoro No. 71, Kenari, Kec. Senen, Kota Jakarta Pusat, Daerah Khusus Ibukota, Jakarta 10430, Indonesia. nikkodarnindro@gmail.com |
Key Words |
Gastrointestinal microbiome; Biodiversity; Intestinal mucosa; Colorectal Cancer; Human |
Core Tip |
Previous studies have reported several specific microbiotas with colorectal cancer. However, these studies were mainly taken from fecal samples instead of colonic mucosal samples and thus could be biased. In addition, studies from Indonesian patients are still very limited and the results may differ from other countries. This study showed that there was a significant difference in the microbiota composition and diversity between colorectal cancer and non-colorectal cancer patients in Indonesia. These results could potentially be used as a diagnostic and prognostic biomarker for colorectal cancer. |
Publish Date |
2025-01-20 07:38 |
Citation |
<p>Darnindro N, Abdullah M, Sukartini N, Rumende CM, Pitarini A, Nursyirwan SA, Fauzi A, Makmun D, Nelwan EJ, Shatri H, Rinaldi I, Tanadi C. Differences in diversity and composition of mucosa-associated colonic microbiota in colorectal cancer and non-colorectal cancer in Indonesia. <i>World J Gastroenterol</i> 2025; 31(7): 100051</p> |
URL |
https://www.wjgnet.com/1007-9327/full/v31/i7/100051.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v31.i7.100051 |