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Articles Published Processes
3/21/2025 6:10:14 AM | Browse: 83 | Download: 395
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Received |
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2024-08-06 13:27 |
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Peer-Review Started |
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2024-08-06 13:27 |
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First Decision by Editorial Office Director |
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2024-11-21 07:24 |
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Return for Revision |
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2024-11-21 07:24 |
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Revised |
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2024-12-04 03:39 |
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Publication Fee Transferred |
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2024-12-05 12:27 |
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Second Decision by Editor |
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2025-01-06 02:43 |
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Second Decision by Editor-in-Chief |
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2025-01-08 07:35 |
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Final Decision by Editorial Office Director |
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2025-02-05 06:14 |
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Articles in Press |
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2025-02-05 06:14 |
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Edit the Manuscript by Language Editor |
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2025-02-12 12:15 |
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Typeset the Manuscript |
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2025-02-17 02:26 |
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Publish the Manuscript Online |
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2025-03-21 06:10 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Basic Study |
| Article Title |
Regulation of lncRNA-ENST on Myc-mediated mitochondrial apoptosis in mesenchymal stem cells: In vitro evidence implicated for acute lung injury therapeutic potential
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ye-Zhou Shen, Guang-Ping Yang, Qi-Min Ma, Yu-Song Wang and Xin Wang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Peak Supporting Clinical Discipline of Shanghai Health Bureau |
2023ZDFC0104 |
| National Key R&D Program of China |
2019YFA0110601 |
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| Corresponding Author |
Xin Wang, Medical Center of Burn Plastic and Wound Repair, The First Affiliated Hospital of Nanchang University, No. 17 Yongwai Zhengjie, Donghu District, Nanchang 330006, Jiangxi Province, China. 18772407841@163.com |
| Key Words |
Long noncoding RNA; Mesenchymal stem cell; Mitochondrial; Apoptosis; Autophagy; Acute lung injury |
| Core Tip |
In this research, we established an acute lung injury (ALI) model and manipulated long noncoding RNA (lncRNA)-ENST levels in bone marrow mesenchymal stem cells (BMSCs) using a lentiviral system. We discovered that lncRNA-ENST00000517482 is a pivotal regulator of BMSC apoptosis and autophagy in ALI. Modulating lncRNA-ENST00000517482 not only reduces apoptosis and induces autophagy in BMSCs but also enhances their viability, offering a novel approach to enhance ALI treatment efficacy via the miR-539/c-MYC axis. |
| Publish Date |
2025-03-21 06:10 |
| Citation |
Shen YZ, Yang GP, Ma QM, Wang YS, Wang X. Regulation of lncRNA-ENST on Myc-mediated mitochondrial apoptosis in mesenchymal stem cells: In vitro evidence implicated for acute lung injury therapeutic potential. World J Stem Cells 2025; 17(3): 100079 |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i3/100079.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i3.100079 |
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